INCAP Studies of Kwashiorkor and Marasmus

This article summarizes thirty years of intensive clinical metabolic and therapeutic studies of the consequences of severe protein deficiency relative to calories, which results in kwashiorkor, and of a balanced deficiency of protein and calories that results in marasmus. Evidence is provided that t...

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Bibliographic Details
Published in:Food and nutrition bulletin 2010-03, Vol.31 (1), p.34-41
Main Authors: Scrimshaw, Nevin S., Viteri, Fernando E.
Format: Article
Language:English
Subjects:
Academies and Institutes - history
Body Height
Central America - epidemiology
Creatinine - urine
History, 20th Century
Humans
Kwashiorkor - diet therapy
Kwashiorkor - etiology
Kwashiorkor - history
Kwashiorkor - physiopathology
Protein-Energy Malnutrition - diet therapy
Protein-Energy Malnutrition - etiology
Protein-Energy Malnutrition - history
Protein-Energy Malnutrition - physiopathology
Severity of Illness Index
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Summary:This article summarizes thirty years of intensive clinical metabolic and therapeutic studies of the consequences of severe protein deficiency relative to calories, which results in kwashiorkor, and of a balanced deficiency of protein and calories that results in marasmus. Evidence is provided that these are two different metabolic diseases, but kwashiorkor is usually superimposed on some degree of chronic marasmus and hence most cases studied were marasmic kwashiorkor. The value of the creatinine/height index to indicate the degree of lean body cell mass with any disease is demonstrated.
ISSN:1564-8265
0379-5721
1564-8265
DOI:10.1177/156482651003100105