MRI and pathological findings of rheumatoid meningitis

Abstract Rheumatoid meningitis (RM) is one of the most severe complications of rheumatoid arthritis. The mortality rate of RM is relatively high and diagnosis can be difficult. We present an 80-year-old woman who was diagnosed with microscopic findings of RM after analysis of biopsy specimens taken...

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Bibliographic Details
Published in:Journal of clinical neuroscience 2010-01, Vol.17 (1), p.129-132
Main Authors: Matsushima, Masaaki, Yaguchi, Hiroaki, Niino, Masaaki, Akimoto-Tsuji, Sachiko, Yabe, Ichiro, Onishi, Katsunori, Sasaki, Hidenao
Format: Article
Language:English
Subjects:
Aged, 80 and over
Arachnoid - pathology
Arachnoid - surgery
Arthritis, Rheumatoid - complications
Biopsy
Brain - pathology
Brain - surgery
Diagnosis, Differential
Dura Mater - pathology
Dura Mater - surgery
Female
Humans
Lymphocyte Activation
Magnetic Resonance Imaging
Meninges - immunology
Meninges - pathology
Meninges - surgery
Meningitis
Meningitis, Aseptic - immunology
Meningitis, Aseptic - pathology
Meningitis, Aseptic - physiopathology
MRI
Neurology
Pathology
Rheumatoid arthritis
Rheumatoid Nodule - etiology
Rheumatoid Nodule - pathology
Rheumatoid Nodule - physiopathology
Steroids - pharmacology
Steroids - therapeutic use
Treatment
Treatment Outcome
Vasculitis - etiology
Vasculitis - pathology
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Summary:Abstract Rheumatoid meningitis (RM) is one of the most severe complications of rheumatoid arthritis. The mortality rate of RM is relatively high and diagnosis can be difficult. We present an 80-year-old woman who was diagnosed with microscopic findings of RM after analysis of biopsy specimens taken from a brain lesion. MRI scanning revealed meningeal enhancement in the brain, and the pathological findings were those of meningeal lymphocytic infiltration, vasculitis and rheumatoid nodules. RM is a treatable disease and in this patient RM was diagnosed on the basis of biopsy findings.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2009.01.033