Evaluating the effectiveness of different treatments of uterine infections in female camels ( Camelus dromedarius)

• Published in: Theriogenology 2010-07, Vol.74 (1), p.40-44
• Main Authors: Ali, A., Al-sobayil, F.A., Al-Hawas, A.
• Format: Article
• Language: English
• Subjects: acriflavine; Acriflavine - therapeutic use; Animals; Anti-Infective Agents - administration & dosage; Anti-Infective Agents - therapeutic use; antibiotics; bacterial infections; Camels; Camelus; cloprostenol; Cloprostenol - therapeutic use; combination drug therapy; complications; Cresols - therapeutic use; dromedaries; Drug Combinations; drug therapy; endometritis; Endometritis - drug therapy; Endometritis - veterinary; Female; female fertility; females; Fertility; Formaldehyde - therapeutic use; gentamicin; Gentamicins - therapeutic use; human chorionic gonadotropin; Infection - drug therapy; Infection - veterinary; Infertility, Female - etiology; Infertility, Female - veterinary; intramuscular injection; intrauterine administration; lotagen; medical treatment; methodology; Parity; Pregnancy; Treatment; Treatment Outcome; Uterine Diseases - complications; Uterine Diseases - drug therapy; Uterine Diseases - veterinary; Uterine infections; Uterus - drug effects
• ISSN: 0093-691X; 1879-3231
• DOI: 10.1016/j.theriogenology.2009.12.017

A total of 480 female camels with a history of conception failure were examined through transrectal palpation, ultrasonography, and vaginal exploration. Animals were categorized according to parity (nulliparous n = 200 vs. multiparous n = 280), and type of uterine infection (endometritis n = 360 vs. metritis n = 120). They were randomly assigned to receive one of three intrauterine treatments: (i) 100 mL acriflavin 0.1% (group 1, n = 170), (ii) 100 mL lotagen 4% (group 2, n = 200), or (iii) 300 mg/100 mL gentamicin sulphate (group 3, n = 110). All groups received 500 μg cloprostenol IM at infusion. Animals were exposed for breeding 7 d later and received 5000 IU hCG im at mating. The criteria for efficacy of treatment were 90 days non-return rate (90 d NRR) and calving rate (CR). The results showed that the 90 d NRR and CR were significantly influenced by parity, type of uterine infection, regime of treatment, and their interactions, P < 0.05. Treatment regimes were approximately equally efficient in treating females with endometritis (90 d NRR were 64%, 53.1% and 53.3% and CR were 58.9%, 49.3%, and 42.5% for groups 1, 2, and 3, respectively, P > 0.05). In contrast, regimes differed in treating those with metritis (90 d NRR were 55.6%, 75%, and 28.6% and CR were 31.6%, 54.8%, and 12.5% for groups 1, 2, and 3, respectively, P < 0.05). In conclusion, a regime consisted of intrauterine lotagen infusion and administration of PGF 2α at infusion and hCG at mating was more efficient for treating female camels with metritis.