Lack of portosystemic bacterial translocation in patients with liver cirrhosis after placement of transjugular shunt

The purpose of this study was to clarify whether bacteria are transferred from the portal venous system into central venous blood during the placement of a transjugular portosystemic stent shunt (TIPSS). TIPSS was created in 30 consecutive cirrhotic patients for recurrent variceal bleeding ( n=12),...

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Bibliographic Details
Published in:European journal of clinical microbiology & infectious diseases 2003-05, Vol.22 (5), p.310-312
Main Authors: COHNEN, M, LÜTHEN, R, DÄUBENER, W, MÖDDER, U
Format: Article
Language:English
Subjects:
Adult
Aged
Ascites
Bacteria
Bacterial Translocation
Biological and medical sciences
Bleeding
Blood
Blood culture
Cirrhosis
Cohort Studies
Contamination
Corynebacterium - physiology
Equipment Contamination
Female
Flora
Follow-Up Studies
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Hypertension, Portal - complications
Hypertension, Portal - microbiology
Hypertension, Portal - surgery
Implants
Liver
Liver Cirrhosis - complications
Liver Cirrhosis - microbiology
Liver Cirrhosis - surgery
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Microbiological analysis
Middle Aged
Mouth
Other diseases. Semiology
Portal vein
Portasystemic Shunt, Transjugular Intrahepatic - adverse effects
Portasystemic Shunt, Transjugular Intrahepatic - methods
Retrospective Studies
Risk Factors
Shunts
Skin
Stents - microbiology
Streptococcus - physiology
Time Factors
Translocation
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Description
Summary:The purpose of this study was to clarify whether bacteria are transferred from the portal venous system into central venous blood during the placement of a transjugular portosystemic stent shunt (TIPSS). TIPSS was created in 30 consecutive cirrhotic patients for recurrent variceal bleeding ( n=12), refractory ascites ( n=16), or hepatorenal syndrome ( n=2). Microbiological analysis was performed prospectively on central venous blood before and on portal venous blood immediately after puncture of the portal vein. Twenty minutes after the placement of TIPSS, another sample of central venous blood was obtained. None of the first two sets of blood cultures showed bacterial growth, so that no bacterial transfer was seen at the time of TIPSS placement. Four of the third sets of blood samples showed skin and mouth flora, interpreted as iatrogenic contamination.
ISSN:0934-9723
1435-4373
DOI:10.1007/s10096-003-0911-9