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Individual Antigenic Specificity of Isolated Antibodies

Antisera produced against certain isolated human antibodies showed clear antigenic differences between these antibodies. Individual antigenic specificity was demonstrated for two anti-A antibodies, one anti-dextran, and one anti-levan antibody. Failure to produce specific antisera in other instances...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1963-06, Vol.140 (3572), p.1218-1219
Main Authors: Kunkel, Henry G., Mannik, Mart, Williams, Ralph C.
Format: Article
Language:English
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Summary:Antisera produced against certain isolated human antibodies showed clear antigenic differences between these antibodies. Individual antigenic specificity was demonstrated for two anti-A antibodies, one anti-dextran, and one anti-levan antibody. Failure to produce specific antisera in other instances appeared to be correlated with a greater heterogeneity of the antibody population used as antigen.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.140.3572.1218