Toxin from Fusarium moniliforme: Effects on Plants and Animals

A mycotoxin-producing strain of Fusarium moniliforme was isolated from southern leaf blight-damaged corn seed. A water-soluble toxin, subsequently purified from the fungus, had an oral median lethal dose of 4.0 milligrams per kilogram in 1-day-old cockerels. The toxin also produced plant growth-regu...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1973-03, Vol.179 (4080), p.1324-1326
Main Authors: Cole, Richard J., Kirksey, Jerry W., Cutler, Horace G., Doupnik, Ben L., Peckham, John C.
Format: Article
Language:English
Subjects:
Corn
Dosage
Fusarium
Mycotoxins
Oxidation
Plants
Sodium
Sulfolobus
Sulfur
Toxins
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Description
Summary:A mycotoxin-producing strain of Fusarium moniliforme was isolated from southern leaf blight-damaged corn seed. A water-soluble toxin, subsequently purified from the fungus, had an oral median lethal dose of 4.0 milligrams per kilogram in 1-day-old cockerels. The toxin also produced plant growth-regulating and phytotoxic effects on plant systems. Physical and chemical data presented for the toxin suggest a structurally new toxin. The trivial name "moniliformin" has been assigned to the toxin.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.179.4080.1324