Rheumatologic sequelae and challenges in organ transplantation

Despite the increasing success of transplantation, graft recipients experience a high burden of musculoskeletal symptoms that may hinder quality of life. Post-transplant musculoskeletal problems may result from sequelae of the organ dysfunction that indicated the transplant or from the subsequent an...

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Bibliographic Details
Published in:Best practice & research. Clinical rheumatology 2010-06, Vol.24 (3), p.329-340
Main Authors: Schwab, Pascale, MD, Lipton, Sarah, MD, Kerr, Gail S., MD, FRCP (Edin)
Format: Article
Language:English
Subjects:
Arthritis - etiology
Arthritis - pathology
Arthritis - physiopathology
avascular necrosis
calcineurin inhibitor pain syndrome
Female
gout
Gout - etiology
Gout - pathology
Gout - physiopathology
Graft vs Host Disease - immunology
graft-versus-host disease
Humans
Immunocompromised Host
Immunosuppressive Agents - adverse effects
Male
Musculoskeletal Diseases - diagnosis
Musculoskeletal Diseases - etiology
Musculoskeletal Diseases - physiopathology
Organ Transplantation - adverse effects
Osteonecrosis - etiology
Osteonecrosis - pathology
Osteonecrosis - physiopathology
osteoporosis
Osteoporosis - etiology
Osteoporosis - pathology
Osteoporosis - physiopathology
Postoperative Complications
Quality of Life
Rheumatology
transplant
Vasculitis - etiology
Vasculitis - pathology
Vasculitis - physiopathology
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Description
Summary:Despite the increasing success of transplantation, graft recipients experience a high burden of musculoskeletal symptoms that may hinder quality of life. Post-transplant musculoskeletal problems may result from sequelae of the organ dysfunction that indicated the transplant or from the subsequent anti-rejection therapy. Rheumatology consultants need to be familiar with the spectrum of musculoskeletal syndromes presenting in these unique patients and their appropriate treatment in the context of complex drug regimens and immunosuppression.
ISSN:1521-6942
1532-1770
DOI:10.1016/j.berh.2009.12.011