The optimal duration and delay of first aid treatment for deep partial thickness burn injuries

Abstract Using our porcine model of deep dermal partial thickness burn injury, various durations (10 min, 20 min, 30 min or 1 h) and delays (immediate, 10 min, 1 h, 3 h) of 15 °C running water first aid were applied to burns and compared to untreated controls. The subdermal temperatures were monitor...

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Bibliographic Details
Published in:Burns 2010-08, Vol.36 (5), p.673-679
Main Authors: Cuttle, Leila, Kempf, Margit, Liu, Pei-Yun, Kravchuk, Olena, Kimble, Roy M
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Biopsy
Body Temperature
Burn
Burns
Burns - pathology
Burns - therapy
Cicatrix - pathology
Cold
Critical Care
Cryotherapy - methods
Delay
Duration
Epithelium - pathology
First Aid
Granulation Tissue - pathology
Human viral diseases
Infectious diseases
Medical sciences
Partial thickness
Porcine model
Swine
Time Factors
Traumas. Diseases due to physical agents
Viral diseases
Viral diseases of the respiratory system and ent viral diseases
Water
Water - administration & dosage
Wound Healing - physiology
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Summary:Abstract Using our porcine model of deep dermal partial thickness burn injury, various durations (10 min, 20 min, 30 min or 1 h) and delays (immediate, 10 min, 1 h, 3 h) of 15 °C running water first aid were applied to burns and compared to untreated controls. The subdermal temperatures were monitored during the treatment and wounds observed weekly for 6 weeks, for re-epithelialisation, wound surface area and cosmetic appearance. At 6 weeks after the burn, tissue biopsies were taken of the scar for histological analysis. Results showed that immediate application of cold running water for 20 min duration is associated with an improvement in re-epithelialisation over the first 2 weeks post-burn and decreased scar tissue at 6 weeks. First aid application of cold water for as little as 10 min duration or up to 1 h delay still provides benefit.
ISSN:0305-4179
1879-1409
DOI:10.1016/j.burns.2009.08.002