Circulating human group A rotavirus genotypes in Malaysia

This study examined the temporal distribution of rotavirus genotypes in Malaysia. Rotaviruses from children with diarrhea admitted to hospitals in 1996 (n = 93) and 2007 (n = 12) in two different regions of Peninsular (West) Malaysia were analyzed for their G and P genotypes using a hemi-nested RT-P...

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Bibliographic Details
Published in:Journal of medical virology 2010-04, Vol.82 (4), p.707-711
Main Authors: Zuridah, H, Kirkwood, C.D, Bogdanovic-Sakran, N, Bishop, R.F, Yap, K.L
Format: Article
Language:English
Subjects:
Biological and medical sciences
Child, Preschool
Diarrhea - epidemiology
Fundamental and applied biological sciences. Psychology
G-type
Genotype
Group a rotavirus
hemi-nested RT-PCR
Hospitalization
human group A rotavirus
Human viral diseases
Humans
Infant
Infectious diseases
Malaysia - epidemiology
Medical sciences
Microbiology
Miscellaneous
Molecular Epidemiology
P-type
Prevalence
RNA-PAGE
Rotavirus
Rotavirus - classification
Rotavirus - genetics
Rotavirus - isolation & purification
Rotavirus Infections - epidemiology
Rotavirus Infections - virology
Viral diseases
Virology
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Summary:This study examined the temporal distribution of rotavirus genotypes in Malaysia. Rotaviruses from children with diarrhea admitted to hospitals in 1996 (n = 93) and 2007 (n = 12) in two different regions of Peninsular (West) Malaysia were analyzed for their G and P genotypes using a hemi-nested RT-PCR assay. In the 2007 samples, the dominant strain was G9P[8]. It was identified in 42% of the samples. Different strains all possessing the G1 genotype were identified in the rest of the samples. In contrast, 81% of the samples collected in 1996 were the G1P[8] strain. No strains with G9 genotype were detected in samples collected in 1996. J. Med. Virol. 82:707-711, 2010.
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.21717