Dexmedetomidine: perioperative applications in children

Summary Dexmedetomidine is a highly specific and selective alpha‐2‐adrenergic agonist with sedative, anxiolytic, and organ protective effects. Its clinical applications in children include premedication, prevention of emergence delirium, as part of multimodal anesthetic regimen and sedation in the p...

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Bibliographic Details
Published in:Pediatric anesthesia 2010-03, Vol.20 (3), p.256-264
Main Author: YUEN, VIVIAN MAN YING
Format: Article
Language:English
Subjects:
Adrenergic alpha-Agonists - administration & dosage
Adrenergic alpha-Agonists - pharmacology
Anxiety - prevention & control
Child
Child, Preschool
Delirium - prevention & control
dexmedetomidine
Dexmedetomidine - administration & dosage
Dexmedetomidine - pharmacology
Humans
Infant
Pain, Postoperative - prevention & control
pediatric anesthesia
perioperative applications
Perioperative Care
Preanesthetic Medication - methods
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Summary:Summary Dexmedetomidine is a highly specific and selective alpha‐2‐adrenergic agonist with sedative, anxiolytic, and organ protective effects. Its clinical applications in children include premedication, prevention of emergence delirium, as part of multimodal anesthetic regimen and sedation in the pediatric intensive care unit. Its role in neuroprotection in children undergoing anesthesia should be explored. In this review, various uses of dexmedetomidine are discussed in detail.
ISSN:1155-5645
1460-9592
DOI:10.1111/j.1460-9592.2009.03207.x