Photodynamic therapy for chronic central serous chorioretinopathy

• Published in: Acta ophthalmologica (Oxford, England) England), 2010-05, Vol.88 (3), p.371-376
• Main Authors: Ruiz‐Moreno, José M., Lugo, Francisco L., Armadá, Felix, Silva, Rufino, Montero, Javier A., Arevalo, J. Fernando, Arias, Luis, Gómez‐Ulla, Francisco
• Format: Article
• Language: English
• Subjects: Adult; Aged; central serous chorioretinopathy; Central Serous Chorioretinopathy - drug therapy; Central Serous Chorioretinopathy - physiopathology; Chronic Disease; Female; Follow-Up Studies; Fovea Centralis - pathology; Humans; Male; Middle Aged; optical coherence tomography; Photochemotherapy; photodynamic therapy; Photosensitizing Agents - therapeutic use; Porphyrins - therapeutic use; retinal pigment epithelium; Retrospective Studies; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity - physiology
• ISSN: 1755-375X; 1755-3768
• DOI: 10.1111/j.1755-3768.2008.01408.x

. Purpose:  This study aimed to evaluate the efficacy of photodynamic therapy (PDT) in treating chronic central serous chorioretinopathy (CSC). Methods:  We describe a non‐randomized, multicentre, interventional case series. A total of 82 eyes of 72 patients with chronic CSC were treated by conventional PDT. LogMAR best corrected visual acuity (BCVA) (ETDRS charts) and central foveal thickness (CFT) measured by optical coherence tomography before and after PDT, number of PDT treatments and complications were used as outcome indicators. Results:  Mean follow‐up was 12 ± 10 months and mean age was 46 ± 10 years. Mean logMAR BCVA changed from 0.53 (standard deviation [SD] 0.43) before PDT to 0.38 (SD 0.41) at 3 months and 0.48 (SD 0.50) at 6 months (p