Paroxysmal atrial fibrillation: which anti-arrhythmic treatment?

Only symptomatic patients with paroxysmal AF will be prescribed anti-arrhythmic drugs in order to prevent recurrences. Anti-arrhythmic drugs' efficacy in maintaining sinus rhythm is around 50 to 70 % at one year. Anti-arrhythmic drug prescription is associated with potentially life-threatening...

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Bibliographic Details
Published in:La Presse médicale (1983) 2010-06, Vol.39 (6), p.688-693
Main Authors: Extramiana, Fabrice, Messali, Anne, Moubarak, Ghassan, Leenhardt, Antoine
Format: Article
Language:fre
Subjects:
Anti-Arrhythmia Agents - therapeutic use
Atrial Fibrillation - drug therapy
Atrial Fibrillation - physiopathology
Humans
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Summary:Only symptomatic patients with paroxysmal AF will be prescribed anti-arrhythmic drugs in order to prevent recurrences. Anti-arrhythmic drugs' efficacy in maintaining sinus rhythm is around 50 to 70 % at one year. Anti-arrhythmic drug prescription is associated with potentially life-threatening pro-arrhythmic effects. Anti-arrhythmic drug prescription should be tailored to each patient after carefully evaluating the risk/benefit ratio. Pulmonary veins isolation might be proposed in case of symptomatic paroxysmal AF after failure of anti-arrhythmic drug therapy.
ISSN:2213-0276
DOI:10.1016/j.lpm.2010.02.043