Loading…
Automated Heart-Type Fatty Acid-Binding Protein Assay for the Early Diagnosis of Acute Myocardial Infarction
We compared an automated quantitative heart-type fatty acid-binding protein (H-FABP) assay with other cardiac-marker assays to examine its usefulness as an early diagnostic marker of acute myocardial infarction (AMI). Serum samples for cardiac troponin T (cTnT), creatine kinase-MB isozyme (CK-MB), m...
Saved in:
Published in: | American journal of clinical pathology 2010-07, Vol.134 (1), p.157-162 |
---|---|
Main Authors: | , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c370t-f3d667c39987b392540b12730a3d4f0c26658210e057d52a1723f86de99e33df3 |
---|---|
cites | cdi_FETCH-LOGICAL-c370t-f3d667c39987b392540b12730a3d4f0c26658210e057d52a1723f86de99e33df3 |
container_end_page | 162 |
container_issue | 1 |
container_start_page | 157 |
container_title | American journal of clinical pathology |
container_volume | 134 |
creator | KIM, Yeongsic KIM, Hyunjung KIM, Soo-Young HAE KYUNG LEE HI JEONG KWON YONG GOO KIM LEE, Jehoon HYUNG MIN KIM BYUNG HAK SO |
description | We compared an automated quantitative heart-type fatty acid-binding protein (H-FABP) assay with other cardiac-marker assays to examine its usefulness as an early diagnostic marker of acute myocardial infarction (AMI). Serum samples for cardiac troponin T (cTnT), creatine kinase-MB isozyme (CK-MB), myoglobin, and H-FABP were obtained from 64 patients with AMI and 53 patients with other conditions (control group). H-FABP was measured by using 2 immunoassays, the H-FABP enzyme-linked immunosorbent assay (ELISA; Biocheck, Foster City, CA) and the H-FABP latex turbidimetric immunoassay (LTIA; HBI, Anyang, Korea). Sensitivities of assays for cTnT, CK-MB, myoglobin, H-FABP (by ELISA), H-FABP (by LTIA), and electrocardiogram (ECG) for the diagnosis of AMI at hospital admission were 39.1%, 59.4%, 64.1%, 68.7%, 70.3%, and 54.7%, respectively. Specificities of cTnT, CK-MB, myoglobin, H-FABP (by ELISA), H-FABP (by LTIA), and ECG were 98.1%, 71.7%, 81.1%, 77.4%, 90.6%, and 92.5%, respectively. The automated H-FABP (by LTIA) is superior to cTnT, CK-MB, myoglobin, and H-FABP (by ELISA) tests for the diagnosis of AMI in patients admitted within 4 hours from the onset of chest pain. |
doi_str_mv | 10.1309/AJCP0F6AXRCJMQQG |
format | article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_733345146</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733345146</sourcerecordid><originalsourceid>FETCH-LOGICAL-c370t-f3d667c39987b392540b12730a3d4f0c26658210e057d52a1723f86de99e33df3</originalsourceid><addsrcrecordid>eNpdkL1vFDEQRy0EIkegp0JuENWGsWd3fS6XI5cPJSJBQaJbzfkjGO2tL7a32P-ei3IEiWqmeO9XPMbeCzgRCPpzd7m6gXXb_fy-ury-vT17wRZC11gpJeVLtgAAWWmh8Ii9yfk3gJBLqF-zIwlN8_gv2NBNJW6pOMvPHaVS3c07x9dUysw7E2z1JYw2jPf8JsXiwsi7nGnmPiZefjl-SmmY-ddA92PMIfPo99ZUHL-eo6FkAw38YvSUTAlxfMteeRqye3e4x-zH-vRudV5dfTu7WHVXlUEFpfJo21YZ1HqpNqhlU8NGSIVAaGsPRrZts5QCHDTKNpKEkuiXrXVaO0Tr8Zh9etrdpfgwuVz6bcjGDQONLk65V4hYN6Ju9yQ8kSbFnJPz_S6FLaW5F9A_Ju7_T7xXPhzGp83W2Wfhb9M98PEAUDY0-ESjCfkfJzWIFhT-AThLhBY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>733345146</pqid></control><display><type>article</type><title>Automated Heart-Type Fatty Acid-Binding Protein Assay for the Early Diagnosis of Acute Myocardial Infarction</title><source>Oxford Journals Online</source><creator>KIM, Yeongsic ; KIM, Hyunjung ; KIM, Soo-Young ; HAE KYUNG LEE ; HI JEONG KWON ; YONG GOO KIM ; LEE, Jehoon ; HYUNG MIN KIM ; BYUNG HAK SO</creator><creatorcontrib>KIM, Yeongsic ; KIM, Hyunjung ; KIM, Soo-Young ; HAE KYUNG LEE ; HI JEONG KWON ; YONG GOO KIM ; LEE, Jehoon ; HYUNG MIN KIM ; BYUNG HAK SO</creatorcontrib><description>We compared an automated quantitative heart-type fatty acid-binding protein (H-FABP) assay with other cardiac-marker assays to examine its usefulness as an early diagnostic marker of acute myocardial infarction (AMI). Serum samples for cardiac troponin T (cTnT), creatine kinase-MB isozyme (CK-MB), myoglobin, and H-FABP were obtained from 64 patients with AMI and 53 patients with other conditions (control group). H-FABP was measured by using 2 immunoassays, the H-FABP enzyme-linked immunosorbent assay (ELISA; Biocheck, Foster City, CA) and the H-FABP latex turbidimetric immunoassay (LTIA; HBI, Anyang, Korea). Sensitivities of assays for cTnT, CK-MB, myoglobin, H-FABP (by ELISA), H-FABP (by LTIA), and electrocardiogram (ECG) for the diagnosis of AMI at hospital admission were 39.1%, 59.4%, 64.1%, 68.7%, 70.3%, and 54.7%, respectively. Specificities of cTnT, CK-MB, myoglobin, H-FABP (by ELISA), H-FABP (by LTIA), and ECG were 98.1%, 71.7%, 81.1%, 77.4%, 90.6%, and 92.5%, respectively. The automated H-FABP (by LTIA) is superior to cTnT, CK-MB, myoglobin, and H-FABP (by ELISA) tests for the diagnosis of AMI in patients admitted within 4 hours from the onset of chest pain.</description><identifier>ISSN: 0002-9173</identifier><identifier>EISSN: 1943-7722</identifier><identifier>DOI: 10.1309/AJCP0F6AXRCJMQQG</identifier><identifier>PMID: 20551280</identifier><identifier>CODEN: AJCPAI</identifier><language>eng</language><publisher>Chicago, IL: American Society of Clinical Pathologists</publisher><subject>Biological and medical sciences ; Cardiology. Vascular system ; Chest Pain - blood ; Chest Pain - diagnosis ; Chest Pain - physiopathology ; Coronary heart disease ; Early Diagnosis ; Electrocardiography ; Fatty Acid Binding Protein 3 ; Fatty Acid-Binding Proteins - blood ; Female ; Heart ; Humans ; Immunoassay - methods ; Investigative techniques, diagnostic techniques (general aspects) ; Latex ; Male ; Medical sciences ; Middle Aged ; Myocardial Infarction - blood ; Myocardial Infarction - diagnosis ; Myocardial Infarction - physiopathology ; Myocarditis. Cardiomyopathies ; Myoglobin - blood ; Nephelometry and Turbidimetry - methods ; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques ; Predictive Value of Tests ; ROC Curve ; Time Factors ; Troponin T - blood</subject><ispartof>American journal of clinical pathology, 2010-07, Vol.134 (1), p.157-162</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-f3d667c39987b392540b12730a3d4f0c26658210e057d52a1723f86de99e33df3</citedby><cites>FETCH-LOGICAL-c370t-f3d667c39987b392540b12730a3d4f0c26658210e057d52a1723f86de99e33df3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22901607$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20551280$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KIM, Yeongsic</creatorcontrib><creatorcontrib>KIM, Hyunjung</creatorcontrib><creatorcontrib>KIM, Soo-Young</creatorcontrib><creatorcontrib>HAE KYUNG LEE</creatorcontrib><creatorcontrib>HI JEONG KWON</creatorcontrib><creatorcontrib>YONG GOO KIM</creatorcontrib><creatorcontrib>LEE, Jehoon</creatorcontrib><creatorcontrib>HYUNG MIN KIM</creatorcontrib><creatorcontrib>BYUNG HAK SO</creatorcontrib><title>Automated Heart-Type Fatty Acid-Binding Protein Assay for the Early Diagnosis of Acute Myocardial Infarction</title><title>American journal of clinical pathology</title><addtitle>Am J Clin Pathol</addtitle><description>We compared an automated quantitative heart-type fatty acid-binding protein (H-FABP) assay with other cardiac-marker assays to examine its usefulness as an early diagnostic marker of acute myocardial infarction (AMI). Serum samples for cardiac troponin T (cTnT), creatine kinase-MB isozyme (CK-MB), myoglobin, and H-FABP were obtained from 64 patients with AMI and 53 patients with other conditions (control group). H-FABP was measured by using 2 immunoassays, the H-FABP enzyme-linked immunosorbent assay (ELISA; Biocheck, Foster City, CA) and the H-FABP latex turbidimetric immunoassay (LTIA; HBI, Anyang, Korea). Sensitivities of assays for cTnT, CK-MB, myoglobin, H-FABP (by ELISA), H-FABP (by LTIA), and electrocardiogram (ECG) for the diagnosis of AMI at hospital admission were 39.1%, 59.4%, 64.1%, 68.7%, 70.3%, and 54.7%, respectively. Specificities of cTnT, CK-MB, myoglobin, H-FABP (by ELISA), H-FABP (by LTIA), and ECG were 98.1%, 71.7%, 81.1%, 77.4%, 90.6%, and 92.5%, respectively. The automated H-FABP (by LTIA) is superior to cTnT, CK-MB, myoglobin, and H-FABP (by ELISA) tests for the diagnosis of AMI in patients admitted within 4 hours from the onset of chest pain.</description><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Chest Pain - blood</subject><subject>Chest Pain - diagnosis</subject><subject>Chest Pain - physiopathology</subject><subject>Coronary heart disease</subject><subject>Early Diagnosis</subject><subject>Electrocardiography</subject><subject>Fatty Acid Binding Protein 3</subject><subject>Fatty Acid-Binding Proteins - blood</subject><subject>Female</subject><subject>Heart</subject><subject>Humans</subject><subject>Immunoassay - methods</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Latex</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - blood</subject><subject>Myocardial Infarction - diagnosis</subject><subject>Myocardial Infarction - physiopathology</subject><subject>Myocarditis. Cardiomyopathies</subject><subject>Myoglobin - blood</subject><subject>Nephelometry and Turbidimetry - methods</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</subject><subject>Predictive Value of Tests</subject><subject>ROC Curve</subject><subject>Time Factors</subject><subject>Troponin T - blood</subject><issn>0002-9173</issn><issn>1943-7722</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNpdkL1vFDEQRy0EIkegp0JuENWGsWd3fS6XI5cPJSJBQaJbzfkjGO2tL7a32P-ei3IEiWqmeO9XPMbeCzgRCPpzd7m6gXXb_fy-ury-vT17wRZC11gpJeVLtgAAWWmh8Ii9yfk3gJBLqF-zIwlN8_gv2NBNJW6pOMvPHaVS3c07x9dUysw7E2z1JYw2jPf8JsXiwsi7nGnmPiZefjl-SmmY-ddA92PMIfPo99ZUHL-eo6FkAw38YvSUTAlxfMteeRqye3e4x-zH-vRudV5dfTu7WHVXlUEFpfJo21YZ1HqpNqhlU8NGSIVAaGsPRrZts5QCHDTKNpKEkuiXrXVaO0Tr8Zh9etrdpfgwuVz6bcjGDQONLk65V4hYN6Ju9yQ8kSbFnJPz_S6FLaW5F9A_Ju7_T7xXPhzGp83W2Wfhb9M98PEAUDY0-ESjCfkfJzWIFhT-AThLhBY</recordid><startdate>20100701</startdate><enddate>20100701</enddate><creator>KIM, Yeongsic</creator><creator>KIM, Hyunjung</creator><creator>KIM, Soo-Young</creator><creator>HAE KYUNG LEE</creator><creator>HI JEONG KWON</creator><creator>YONG GOO KIM</creator><creator>LEE, Jehoon</creator><creator>HYUNG MIN KIM</creator><creator>BYUNG HAK SO</creator><general>American Society of Clinical Pathologists</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100701</creationdate><title>Automated Heart-Type Fatty Acid-Binding Protein Assay for the Early Diagnosis of Acute Myocardial Infarction</title><author>KIM, Yeongsic ; KIM, Hyunjung ; KIM, Soo-Young ; HAE KYUNG LEE ; HI JEONG KWON ; YONG GOO KIM ; LEE, Jehoon ; HYUNG MIN KIM ; BYUNG HAK SO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c370t-f3d667c39987b392540b12730a3d4f0c26658210e057d52a1723f86de99e33df3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Chest Pain - blood</topic><topic>Chest Pain - diagnosis</topic><topic>Chest Pain - physiopathology</topic><topic>Coronary heart disease</topic><topic>Early Diagnosis</topic><topic>Electrocardiography</topic><topic>Fatty Acid Binding Protein 3</topic><topic>Fatty Acid-Binding Proteins - blood</topic><topic>Female</topic><topic>Heart</topic><topic>Humans</topic><topic>Immunoassay - methods</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Latex</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - blood</topic><topic>Myocardial Infarction - diagnosis</topic><topic>Myocardial Infarction - physiopathology</topic><topic>Myocarditis. Cardiomyopathies</topic><topic>Myoglobin - blood</topic><topic>Nephelometry and Turbidimetry - methods</topic><topic>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</topic><topic>Predictive Value of Tests</topic><topic>ROC Curve</topic><topic>Time Factors</topic><topic>Troponin T - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KIM, Yeongsic</creatorcontrib><creatorcontrib>KIM, Hyunjung</creatorcontrib><creatorcontrib>KIM, Soo-Young</creatorcontrib><creatorcontrib>HAE KYUNG LEE</creatorcontrib><creatorcontrib>HI JEONG KWON</creatorcontrib><creatorcontrib>YONG GOO KIM</creatorcontrib><creatorcontrib>LEE, Jehoon</creatorcontrib><creatorcontrib>HYUNG MIN KIM</creatorcontrib><creatorcontrib>BYUNG HAK SO</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KIM, Yeongsic</au><au>KIM, Hyunjung</au><au>KIM, Soo-Young</au><au>HAE KYUNG LEE</au><au>HI JEONG KWON</au><au>YONG GOO KIM</au><au>LEE, Jehoon</au><au>HYUNG MIN KIM</au><au>BYUNG HAK SO</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Automated Heart-Type Fatty Acid-Binding Protein Assay for the Early Diagnosis of Acute Myocardial Infarction</atitle><jtitle>American journal of clinical pathology</jtitle><addtitle>Am J Clin Pathol</addtitle><date>2010-07-01</date><risdate>2010</risdate><volume>134</volume><issue>1</issue><spage>157</spage><epage>162</epage><pages>157-162</pages><issn>0002-9173</issn><eissn>1943-7722</eissn><coden>AJCPAI</coden><abstract>We compared an automated quantitative heart-type fatty acid-binding protein (H-FABP) assay with other cardiac-marker assays to examine its usefulness as an early diagnostic marker of acute myocardial infarction (AMI). Serum samples for cardiac troponin T (cTnT), creatine kinase-MB isozyme (CK-MB), myoglobin, and H-FABP were obtained from 64 patients with AMI and 53 patients with other conditions (control group). H-FABP was measured by using 2 immunoassays, the H-FABP enzyme-linked immunosorbent assay (ELISA; Biocheck, Foster City, CA) and the H-FABP latex turbidimetric immunoassay (LTIA; HBI, Anyang, Korea). Sensitivities of assays for cTnT, CK-MB, myoglobin, H-FABP (by ELISA), H-FABP (by LTIA), and electrocardiogram (ECG) for the diagnosis of AMI at hospital admission were 39.1%, 59.4%, 64.1%, 68.7%, 70.3%, and 54.7%, respectively. Specificities of cTnT, CK-MB, myoglobin, H-FABP (by ELISA), H-FABP (by LTIA), and ECG were 98.1%, 71.7%, 81.1%, 77.4%, 90.6%, and 92.5%, respectively. The automated H-FABP (by LTIA) is superior to cTnT, CK-MB, myoglobin, and H-FABP (by ELISA) tests for the diagnosis of AMI in patients admitted within 4 hours from the onset of chest pain.</abstract><cop>Chicago, IL</cop><pub>American Society of Clinical Pathologists</pub><pmid>20551280</pmid><doi>10.1309/AJCP0F6AXRCJMQQG</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0002-9173 |
ispartof | American journal of clinical pathology, 2010-07, Vol.134 (1), p.157-162 |
issn | 0002-9173 1943-7722 |
language | eng |
recordid | cdi_proquest_miscellaneous_733345146 |
source | Oxford Journals Online |
subjects | Biological and medical sciences Cardiology. Vascular system Chest Pain - blood Chest Pain - diagnosis Chest Pain - physiopathology Coronary heart disease Early Diagnosis Electrocardiography Fatty Acid Binding Protein 3 Fatty Acid-Binding Proteins - blood Female Heart Humans Immunoassay - methods Investigative techniques, diagnostic techniques (general aspects) Latex Male Medical sciences Middle Aged Myocardial Infarction - blood Myocardial Infarction - diagnosis Myocardial Infarction - physiopathology Myocarditis. Cardiomyopathies Myoglobin - blood Nephelometry and Turbidimetry - methods Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Predictive Value of Tests ROC Curve Time Factors Troponin T - blood |
title | Automated Heart-Type Fatty Acid-Binding Protein Assay for the Early Diagnosis of Acute Myocardial Infarction |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T08%3A40%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Automated%20Heart-Type%20Fatty%20Acid-Binding%20Protein%20Assay%20for%20the%20Early%20Diagnosis%20of%20Acute%20Myocardial%20Infarction&rft.jtitle=American%20journal%20of%20clinical%20pathology&rft.au=KIM,%20Yeongsic&rft.date=2010-07-01&rft.volume=134&rft.issue=1&rft.spage=157&rft.epage=162&rft.pages=157-162&rft.issn=0002-9173&rft.eissn=1943-7722&rft.coden=AJCPAI&rft_id=info:doi/10.1309/AJCP0F6AXRCJMQQG&rft_dat=%3Cproquest_cross%3E733345146%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c370t-f3d667c39987b392540b12730a3d4f0c26658210e057d52a1723f86de99e33df3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=733345146&rft_id=info:pmid/20551280&rfr_iscdi=true |