Anti-inflammatory activity of roots of Ecbolium viride (Forsk) Merrill

Traditionally the aqueous extracts of dried roots of the plant Ecbolium viride are used for menorrhagia, rheumatism and jaundice. The aim was to evaluate the anti-inflammatory activity of Ecbolium viride extract in an in vivo model. The ethyl acetate fraction of Ecbolium viride root extract was prep...

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Bibliographic Details
Published in:Journal of ethnopharmacology 2010-03, Vol.128 (1), p.248-250
Main Authors: Lalitha, K.G., Sethuraman, M.G.
Format: Article
Language:English
Subjects:
Acanthaceae
Acanthaceae - chemistry
animal models
Animals
Anti-inflammatory activity
Anti-Inflammatory Agents - pharmacology
Anti-Inflammatory Agents - therapeutic use
Biological and medical sciences
Carrageenan
Cotton pellet granuloma
Ecbolium viride
edema
General pharmacology
granuloma
in vivo studies
Inflammation - drug therapy
Medical sciences
medicinal plants
medicinal properties
oral administration
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
plant extracts
Plant Extracts - pharmacology
Plant Roots - chemistry
protective effect
Rats
Rats, Wistar
roots
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Summary:Traditionally the aqueous extracts of dried roots of the plant Ecbolium viride are used for menorrhagia, rheumatism and jaundice. The aim was to evaluate the anti-inflammatory activity of Ecbolium viride extract in an in vivo model. The ethyl acetate fraction of Ecbolium viride root extract was prepared and administered orally to rats. The anti-inflammatory activity of Ecbolium viride was determined by carrageenan-induced paw edema and cotton pellet granuloma models. Oral administration of Ecbolium viride extract reduced inflammation significantly ( P < 0.01) in both the carageenan paw edema and the cotton pellet granuloma models. The results of the study supported the traditional use of Ecbolium viride in the treatment for inflammatory disease.
ISSN:0378-8741
1872-7573
DOI:10.1016/j.jep.2009.12.030