A conventional route to scalable morphology-controlled regular structures and their superhydrophobic/hydrophilic properties for biochips application

We use a conventional and straightforward route to fabricate scalable morphology-controlled regular structures. This route is based on the etching of PDMS microlens array in CF4 and CF4/O2 plasma. PDMS microlens array can be changed to regularly isolated microdot structures array in CF4 plasma. Micr...

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Bibliographic Details
Published in:Lab on a chip 2009-01, Vol.9 (15), p.2140-2144
Main Authors: Ren, Hong-Xuan, Chen, Xing, Huang, Xing-Jiu, Im, Maesoon, Kim, Dong-Haan, Lee, Joo-Hyung, Yoon, Jun-Bo, Gu, Ning, Liu, Jin-Huai, Choi, Yang-Kyu
Format: Article
Language:English
Subjects:
Biosensing Techniques - instrumentation
Biosensing Techniques - methods
Dimethylpolysiloxanes - chemistry
DNA, Single-Stranded - analysis
Hydrocarbons, Fluorinated - chemistry
Hydrophobic and Hydrophilic Interactions
Lenses
Microfluidic Analytical Techniques - instrumentation
Microfluidic Analytical Techniques - methods
Oligonucleotide Array Sequence Analysis
Oxygen - chemistry
Wettability
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Summary:We use a conventional and straightforward route to fabricate scalable morphology-controlled regular structures. This route is based on the etching of PDMS microlens array in CF4 and CF4/O2 plasma. PDMS microlens array can be changed to regularly isolated microdot structures array in CF4 plasma. Microbowl shaped structures array can be reached in CF4/O2 plasma. Moreover, a set of structures after CF4 plasma treatment display superhydrophobicity, while a set of structures after CF4/O2 plasma treatment present hydrophilicity. DNA molecules can be readily enriched on the hydrophilic surface. We believe that the regular structure array surfaces provide a useful inspiration towards biomolecular detection and transportation in biochips.
ISSN:1473-0197
1473-0189
DOI:10.1039/b905804d