Clinical and laboratory profile of pediatric and adolescent patients with type 1 diabetes

To evaluate clinical and laboratory profiles of patients with type 1 diabetes mellitus in three public hospitals in São Paulo, Brazil, since type 1 diabetes mellitus is a chronic illness that occurs mainly in the pediatric age group in the Brazilian population. Cross-sectional study with patients fo...

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Bibliographic Details
Published in:Jornal de pediatria 2009-11, Vol.85 (6), p.490-494
Main Authors: Jose, Laura Pereira da Silva, Cardoso-Demartini, Adriane de A, Liberatore Junior, Raphael D R, Paulino, Maria Fernanda Vanti Macedo, Lemos-Marini, Sofia Helena Valente de, Guerra-Júnior, Gil, Rodrigues, Albertina Gomes
Format: Article
Language:eng ; por
Subjects:
Adolescent
Adult
Brazil
Child
Child, Preschool
Diabetes Mellitus, Type 1 - blood
Diabetes Mellitus, Type 1 - diagnosis
Diabetes Mellitus, Type 1 - drug therapy
Epidemiologic Methods
Female
Glycated Hemoglobin A - analysis
Hospitals, Public
Humans
Hypoglycemic Agents - administration & dosage
Insulin - administration & dosage
Male
Young Adult
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Summary:To evaluate clinical and laboratory profiles of patients with type 1 diabetes mellitus in three public hospitals in São Paulo, Brazil, since type 1 diabetes mellitus is a chronic illness that occurs mainly in the pediatric age group in the Brazilian population. Cross-sectional study with patients followed up in reference centers in São José do Rio Preto (FAMERP), Campinas (UNICAMP) and São Paulo (Conjunto Hospitalar do Mandaqui). Data about gender, age, diabetes duration, daily insulin dose, number of daily insulin injections, and glycosylated hemoglobin (HbA1c) were analyzed. Two hundred and thirty-nine patients (131 females) were evaluated; mean age was 13.1+/-4.7 years and mean diabetes duration was 6.6+/-4.2 years. Daily insulin doses ranged from 0.1 to 1.78 units/kg/day (0.88+/-0.28), and 180 (74.7%) patients had two daily injections. HbA1c ranged from 4.6 to 17.9% (10.0+/-2.3%). Although the hospitals included in this study are excellence centers for the follow-up of patients with diabetes in three municipalities in the state of São Paulo, one of the most developed states in Brazil, blood glucose control evaluated according to HbA1c was not adequate. Findings confirm that, despite the efforts of all the professionals involved, great challenges still lie ahead.
ISSN:0021-7557
1678-4782
DOI:10.2223/JPED.1942