In vitro activity of nine antifungal agents against clinical isolates of Aspergillus calidoustus

This study analyzes Aspergillus isolates from the Spanish National Centre for Microbiology collection, which were identified morphologically as members of Aspergillus section Usti. Strains were identified through the analysis of the Internal Transcribed Spacer regions and partial β tubulin gene sequ...

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Bibliographic Details
Published in:Medical mycology (Oxford) 2010-02, Vol.48 (1), p.97-102
Main Authors: Alastruey-Izquierdo, Ana, Cuesta, Isabel, Houbraken, Jos, Cuenca-Estrella, Manuel, Monzón, Araceli, Rodriguez-Tudela, Juan L.
Format: Article
Language:English
Subjects:
Antifungal Agents - pharmacology
Aspergillosis - microbiology
Aspergillus - classification
Aspergillus - drug effects
Aspergillus - isolation & purification
DNA, Fungal - chemistry
DNA, Fungal - genetics
DNA, Ribosomal - chemistry
DNA, Ribosomal - genetics
DNA, Ribosomal Spacer - chemistry
DNA, Ribosomal Spacer - genetics
Fungal Proteins - genetics
Humans
Microbial Sensitivity Tests
Molecular Sequence Data
Sequence Analysis, DNA
Spain
Tubulin - genetics
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Summary:This study analyzes Aspergillus isolates from the Spanish National Centre for Microbiology collection, which were identified morphologically as members of Aspergillus section Usti. Strains were identified through the analysis of the Internal Transcribed Spacer regions and partial β tubulin gene sequences. One Aspergillus pseudodeflectus isolate and eight Aspergillus calidoustus isolates were detected in this panel of clinical strains. Terbinafine and the echinocandins micafungin and anidulafungin, were the drugs most active against these species.
ISSN:1369-3786
1460-2709
DOI:10.3109/13693780902803040