Case Study of Tc-99m HMPAO Brain SPECT Imaging in a Patient With Hepatic Encephalopathy and Carotid Artery Stenosis

A patient with hepatic encephalopathy is described. An initial SPECT using Tc-99m HMPAO was performed to evaluate relative brain perfusion. The initial brain SPECT images revealed decreased perfusion in the left frontal temporal lobe region. A subsequent carotid Doppler study revealed left-sided car...

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Bibliographic Details
Published in:Clinical nuclear medicine 2010-05, Vol.35 (5), p.317-320
Main Authors: Blend, Michael J, Rohany, Mehdi, Jones-Martinez, Nicole, De Leon, Ovidio A
Format: Article
Language:English
Subjects:
Adult
Brain - diagnostic imaging
Carotid Stenosis - complications
Carotid Stenosis - diagnostic imaging
Female
Hepatic Encephalopathy - complications
Hepatic Encephalopathy - diagnostic imaging
Humans
Technetium Tc 99m Exametazime
Tomography, Emission-Computed, Single-Photon - methods
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Summary:A patient with hepatic encephalopathy is described. An initial SPECT using Tc-99m HMPAO was performed to evaluate relative brain perfusion. The initial brain SPECT images revealed decreased perfusion in the left frontal temporal lobe region. A subsequent carotid Doppler study revealed left-sided carotid artery stenosis. After appropriate medical treatment for elevated NH3 levels and reversal of the patientʼs symptoms, repeat SPECT brain images showed a normal pattern of activity. The possible causes and significance for these image findings are discussed.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0b013e3181d62515