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Association between neuropsychiatric morbidity and streptococcal infections in children

We conducted a case control study to study the association between neuropsychiatric morbidity and group A streptococcal infections in children. Twenty two cases of neuropsychiatric morbidity were compared with 64 controls. Fourteen (63.6%) of the 22 cases were positive for ASO and/or ADNB while 21 o...

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Bibliographic Details
Published in:Indian pediatrics 2010-02, Vol.47 (2), p.168-170
Main Authors: Viswanathan, S., Moses, P. D., Varkki, S., Russell, P. S., Brahmadathan, K. N.
Format: Article
Language:English
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Summary:We conducted a case control study to study the association between neuropsychiatric morbidity and group A streptococcal infections in children. Twenty two cases of neuropsychiatric morbidity were compared with 64 controls. Fourteen (63.6%) of the 22 cases were positive for ASO and/or ADNB while 21 of the 64 controls (32.8%) were positive for either or both antibodies (OR = 3.428; CI: 1.15 −10.18; P =0.026). We conclude that there is a statistically significant association between neuropsychiatric morbidity and streptococcal infection in children.
ISSN:0019-6061
0974-7559
DOI:10.1007/s13312-010-0026-1