Perioperative seizures following deep brain stimulation in patients with multiple sclerosis

Following a total of 386 deep brain stimulation (DBS) procedures in Oxford, only two seizures have been recorded in the peri-operative period. Both patients had MS and underwent thalamic DBS for tremor and these 2 cases are presented here. The incidence of peri-operative seizures in MS patients unde...

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Bibliographic Details
Published in:British journal of neurosurgery 2010-06, Vol.24 (3), p.304-305
Main Authors: Johnson, Reuben D., Qadri, Syed R., Joint, C., Moir, L., Green, A. L., Aziz, T. Z.
Format: Article
Language:English
Subjects:
Adult
Brain
Convulsions & seizures
Deep Brain Stimulation - adverse effects
Deep Brain Stimulation - methods
Female
Humans
Multiple sclerosis
Multiple Sclerosis - complications
Seizures - etiology
Seizures - surgery
Treatment Outcome
Tremor - complications
Tremor - therapy
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Summary:Following a total of 386 deep brain stimulation (DBS) procedures in Oxford, only two seizures have been recorded in the peri-operative period. Both patients had MS and underwent thalamic DBS for tremor and these 2 cases are presented here. The incidence of peri-operative seizures in MS patients undergoing DBS procedures is more than 8-fold greater than that expected for patients undergoing DBS procedures. Further experience with DBS procedures in MS patients is needed to determine whether there is a role for peri-operative anticonvulsants in these patients.
ISSN:0268-8697
1360-046X
DOI:10.3109/02688690903577631