Rose bengal staining of the temporal conjunctiva differentiates Sjögren's syndrome from keratoconjunctivitis sicca

To compare the clinical presentation of 231 patients with primary Sjögren's syndrome (pSS) with 89 patients with aqueous-deficient dry eye (keratoconjunctivitis sicca; KCS), to determine those procedures that best differentiate these groups in the eye care clinic. The records of all patients se...

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Bibliographic Details
Published in:Investigative ophthalmology & visual science 2010-05, Vol.51 (5), p.2381-2387
Main Authors: Caffery, Barbara, Simpson, Trefford, Wang, Sunny, Bailey, Denis, McComb, John, Rutka, John, Slomovic, Allan, Bookman, Arthur
Format: Article
Language:English
Subjects:
Algorithms
Conjunctiva - pathology
Female
Fluorescent Dyes
Humans
Keratoconjunctivitis Sicca - diagnosis
Male
Middle Aged
Rose Bengal
Sjogren's Syndrome - diagnosis
Staining and Labeling
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Summary:To compare the clinical presentation of 231 patients with primary Sjögren's syndrome (pSS) with 89 patients with aqueous-deficient dry eye (keratoconjunctivitis sicca; KCS), to determine those procedures that best differentiate these groups in the eye care clinic. The records of all patients seen at the University Health Network Sjögren's Syndrome Clinic from October 1992 to July 2006 were reviewed and documented. The diagnosis of pSS was based on the AECC (American European Consensus Criteria) of 2002. KCS control subjects were non-SS patients with symptoms of dry eye and Schirmer scores of
ISSN:1552-5783
1552-5783
DOI:10.1167/iovs.09-4188