Assessment of Extravascular Lung Water and Cardiac Function in Trimix SCUBA Diving

• Published in: Medicine and science in sports and exercise 2010-06, Vol.42 (6), p.1054-1061
• Main Authors: MARINOVIC, Jasna, LJUBKOVIC, Marko, OBAD, Ante, BRESKOVIC, Toni, SALAMUNIC, Ilza, DENOBLE, Petar J, DUJIC, Zeljko
• Format: Article
• Language: English
• Subjects: Adult; Biological and medical sciences; Blood Pressure; Decompression Sickness - blood; Decompression Sickness - diagnostic imaging; Diving - adverse effects; Diving - physiology; Echocardiography; Extravascular Lung Water - diagnostic imaging; Extravascular Lung Water - physiology; Fundamental and applied biological sciences. Psychology; Helium - adverse effects; Helium - physiology; Humans; Middle Aged; Natriuretic Peptide, Brain - blood; Nitrogen - adverse effects; Nitrogen - physiology; Oxygen - adverse effects; Oxygen - physiology; Peptide Fragments - blood; Pulmonary Artery; Space life sciences; Stroke Volume - physiology; Ventricular Dysfunction, Left - diagnostic imaging; Ventricular Dysfunction, Left - etiology; Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports
• ISSN: 0195-9131; 1530-0315
• DOI: 10.1249/MSS.0b013e3181c5b8a8

An increasing number of recreational self-contained underwater breathing apparatus (SCUBA) divers use trimix of oxygen, helium, and nitrogen for dives deeper than 60 m of sea water. Although it was seldom linked to the development of pulmonary edema, whether SCUBA diving affects the extravascular lung water (EVLW) accumulation is largely unexplored. Seven divers performed six dives on consecutive days using compressed gas mixture of oxygen, helium, and nitrogen (trimix), with diving depths ranging from 55 to 80 m. The echocardiographic parameters (bubble grade, lung comets, mean pulmonary arterial pressure (PAP), and left ventricular function) and the blood levels of the N-terminal part of pro-brain natriuretic peptide (NT-proBNP) were assessed before and after each dive. Venous gas bubbling was detected after each dive with mean probability of decompression sickness ranging from 1.77% to 3.12%. After each dive, several ultrasonographically detected lung comets rose significantly, which was paralleled by increased pulmonary artery pressure (PAP) and decreased left ventricular contractility (reduced ejection fraction at higher end-systolic and end-diastolic volumes) as well as the elevated NT-proBNP. The number of ultrasound lung comets and mean PAP did not return to baseline values after each dive. This is the first report that asymptomatic SCUBA dives are associated with accumulation of EVLW with concomitant increase in PAP, diminished left ventricular contractility, and increased release of NT-proBNP, suggesting a significant cardiopulmonary strain. EVLW and PAP did not return to baseline during repetitive dives, indicating possible cumulative effect with increasing the risk for pulmonary edema.