Effect of exercise training on aging-induced changes in rat papillary muscle

The effects of aging on papillary muscle have been widely demonstrated, but no data on the effects of exercise on the age-related changes are available. To analyze the effects of aging on the morphological and quantitative properties of papillary muscle and investigate whether a long-term moderate e...

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Bibliographic Details
Published in:Arquivos brasileiros de cardiologia 2009-05, Vol.92 (5), p.356-392
Main Authors: Maifrino, Laura Beatriz Mesiano, Araújo, Rubens Correa, Faccini, Cristiane Castro, Liberti, Edson Aparecido, Gama, Eliane Florêncio, Ribeiro, Antonio Augusto Coppi Maciel, Souza, Romeu Rodrigues de
Format: Article
Language:English
Subjects:
Aging - metabolism
Analysis of Variance
Animals
Heart Ventricles - ultrastructure
Male
Myocytes, Cardiac - physiology
Myocytes, Cardiac - ultrastructure
Papillary Muscles - physiology
Papillary Muscles - ultrastructure
Physical Conditioning, Animal - methods
Rats
Rats, Wistar
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Summary:The effects of aging on papillary muscle have been widely demonstrated, but no data on the effects of exercise on the age-related changes are available. To analyze the effects of aging on the morphological and quantitative properties of papillary muscle and investigate whether a long-term moderate exercise program would exert a protective effect against the effects of aging. We used electron microscopy to study the density of myocytes, capillaries and connective tissue and the cross-sectional area of myocytes of the papillary muscle of the left ventricle of 6- and 13-month-old untrained and exercised Wistar rats. As expected, the volume density of myocytes declined significantly (p
ISSN:1678-4170