Adiponectin levels and its association with hyperglycaemia in adult Filipino participants in the 2003—04 National Nutrition and Health Survey

Our objective was to determine the association of serum adiponectin levels with the presence of IFG or DM in Filipinos. This case control study used sera of adult participants in the Philippines’ NNHeS: 2003—04. Subjects were divided into: normoglycaemic control, impaired fasting glucose, and type 2...

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Bibliographic Details
Published in:Diabetes & vascular disease research 2009-10, Vol.6 (4), p.231-237
Main Authors: Paz-Pacheco, Elizabeth, Lim-Abrahan, Mary Anne, Sy, Rosa Allyn G., Jasul, Gabriel V., Sison, Cherrie Mae C., Laurel, Aurora F.
Format: Article
Language:English
Subjects:
Adiponectin - blood
Adult
Aged
Asian Continental Ancestry Group - statistics & numerical data
Biomarkers - blood
Blood Glucose - metabolism
Body Mass Index
Case-Control Studies
Chi-Square Distribution
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - ethnology
Diabetes Mellitus, Type 2 - physiopathology
Down-Regulation
Fasting - blood
Female
Health Surveys
Humans
Hyperglycemia - blood
Hyperglycemia - ethnology
Hyperglycemia - physiopathology
Male
Middle Aged
Philippines - epidemiology
Prediabetic State - blood
Prediabetic State - ethnology
Prediabetic State - physiopathology
Time Factors
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Summary:Our objective was to determine the association of serum adiponectin levels with the presence of IFG or DM in Filipinos. This case control study used sera of adult participants in the Philippines’ NNHeS: 2003—04. Subjects were divided into: normoglycaemic control, impaired fasting glucose, and type 2 diabetes mellitus. Seventy-seven prediabetic and 83 diabetic subjects were included in the prediabetic and diabetic groups, respectively. There was no significant difference in adiponectin values between control and prediabetic subjects. Diabetic subjects had significantly lower mean serum adiponectin levels (10.7 versus 14.2 µg/ml, p=0.0198) compared with age- and BMI-matched control subjects. Diabetic subjects were found most frequently (43.53%) in the lowest tertile (1.6—7.2 µg/ml) and least frequently (20%) in the highest tertile (14—84 µg/ml) of adiponectin values. We conclude that Filipinos with diabetes mellitus had significantly lower adiponectin levels compared with normoglycaemic subjects.
ISSN:1479-1641
1752-8984
DOI:10.1177/1479164109344933