Intrauterine device or estrogen treatment after hysteroscopic uterine septum resection

• Published in: International journal of gynecology and obstetrics 2010-06, Vol.109 (3), p.226-229
• Main Authors: Tonguc, Esra Ayşin, Var, Turgut, Yilmaz, Nafiye, Batioglu, Sertac
• Format: Article
• Language: English
• Subjects: Adhesions; Adult; Biological and medical sciences; Combined Modality Therapy; Contraceptives, Oral, Combined - administration & dosage; Contraceptives, Oral, Combined - therapeutic use; Drug Combinations; Estradiol - administration & dosage; Estradiol - analogs & derivatives; Estradiol - therapeutic use; Estrogen treatment; Female; Gynecology. Andrology. Obstetrics; Humans; Hysteroscopic metroplasty; Hysteroscopic uterine septum resection; Hysteroscopy - methods; Intrauterine device; Intrauterine Devices; Medical sciences; Norgestrel - administration & dosage; Norgestrel - therapeutic use; Obstetrics and Gynecology; Pregnancy; Pregnancy Outcome; Prospective Studies; Single-Blind Method; Tissue Adhesions - etiology; Tissue Adhesions - prevention & control; Uterus - abnormalities; Uterus - surgery; Young Adult
• ISSN: 0020-7292; 1879-3479
• DOI: 10.1016/j.ijgo.2009.12.015

Abstract Objective To investigate the effects on adhesion formation and pregnancy maintenance of an intrauterine device (IUD) and/or estrogen treatment after hysteroscopic septum resection. Methods After septum resection 100 women received either no treatment, or estrogens, or an IUD, or an IUD plus estrogens (n = 25 per group). Most were later checked hysteroscopically for uterine cavity adhesions. All pregnancies occurring during the study period were recorded. Results Adhesions developed in 1 of 19 (5.3%) of the untreated women, 3 of 25 (12%) of the women treated with an IUD plus estrogens, 2 of 19 (10.5%) of the women treated with an IUD only, and none of the women treated with estrogens only. None of the differences, however, were significant. Regarding pregnancy, the differences between groups were also not significant. Conclusion Neither IUD placement, nor estrogen treatment, nor both were found to prevent intrauterine adhesions or facilitate pregnancy after hysteroscopic uterine septum resection.