Circulating Tumor Cells in Solid Tumor in Metastatic and Localized Stages

The aim of this study was the detection of circulating tumor cells (CTC) in three tumor types of epithelial origin. Patients and Methods: Four hundred and thirty-eight patients with breast cancer (56.2% localized and 43.8% metastatic), 195 with colorectal tumors (84.1% localized and 15.9% metastatic...

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Bibliographic Details
Published in:Anticancer research 2009-11, Vol.29 (11), p.4839-4843
Main Authors: LUISA M. MAESTRO, JAVIER SASTRE, SARA B. RAFAEL, SILVIA B. VEGANZONES, MARTA VIDAURRETA, MIGUEL MARTÍN, CARLOS OLIVIER, VIRGINIA B. DE LA ORDEN, JOSE ANGEL GARCIA-SAENZ, ROSARIO ALFONSO, MANUEL ARROYO, EDUARDO DIAZ-RUBIO
Format: Article
Language:English
Subjects:
Adult
Breast Neoplasms - blood
Breast Neoplasms - pathology
Case-Control Studies
Colorectal Neoplasms - blood
Colorectal Neoplasms - pathology
Female
Humans
Male
Neoplasm Metastasis
Neoplasm Staging
Neoplastic Cells, Circulating - pathology
Prospective Studies
Prostatic Neoplasms - blood
Prostatic Neoplasms - pathology
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Summary:The aim of this study was the detection of circulating tumor cells (CTC) in three tumor types of epithelial origin. Patients and Methods: Four hundred and thirty-eight patients with breast cancer (56.2% localized and 43.8% metastatic), 195 with colorectal tumors (84.1% localized and 15.9% metastatic) and 50 with prostate cancer (52% localized and 48% metastatic) took part in this study. CTC quantification was performed using the CellSpotter Analyzer (Veridex® LLC). Results: 31.5% of patients with cancer had ≥2 CTCs/7.5 mL but none of the healthy volunteers were above this level (p
ISSN:0250-7005
1791-7530