Green tea consumption and the risk of liver cancer in Japan: the Ohsaki Cohort study

Objectives To investigate the association between green tea consumption and liver cancer incidence. Methods We prospectively followed 41,761 Japanese adults aged 40-79 years, without a history of cancer at the baseline or any missing data for green tea consumption frequency. Cox proportional hazards...

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Bibliographic Details
Published in:Cancer causes & control 2009-12, Vol.20 (10), p.1939-1945
Main Authors: Ui, Akane, Kuriyama, Shinichi, Kakizaki, Masako, Sone, Toshimasa, Nakaya, Naoki, Ohmori-Matsuda, Kaori, Hozawa, Atsushi, Nishino, Yoshikazu, Tsuji, Ichiro
Format: Article
Language:English
Subjects:
Adult
Aged
Alcohol drinking
Beverages
Biomedical and Life Sciences
Biomedicine
Cancer
Cancer Research
Carcinoma - epidemiology
Carcinoma - etiology
Cigarette smoking
Cohort Studies
Drinking Behavior - physiology
Eating - physiology
Epidemiology
Female
Green teas
Hematology
Humans
Incidence
Japan - epidemiology
Liver cancer
Liver diseases
Liver Neoplasms - epidemiology
Liver Neoplasms - etiology
Male
Men
Middle Aged
Nutrition Surveys
Oncology
Original Paper
Polyphenols
Public Health
Risk Factors
Tea
Vegetables
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Summary:Objectives To investigate the association between green tea consumption and liver cancer incidence. Methods We prospectively followed 41,761 Japanese adults aged 40-79 years, without a history of cancer at the baseline or any missing data for green tea consumption frequency. Cox proportional hazards models were used to calculate hazard ratios (HR) with 95% confidence intervals (CI), adjusted for age, alcohol drinking, smoking, the consumption of coffee, vegetables, dairy products, fruit, fish, and soybean. Results Over 9 years of follow-up, among 325,947 accrued person-years, the total incidence of liver cancer was 247 cases. We found that green tea consumption was inversely associated with the incidence of liver cancer. In men, the multivariate-adjusted HRs (95% CIs) for liver cancer incidence with different green tea consumption categories were 1.00 (reference) for
ISSN:0957-5243
1573-7225
DOI:10.1007/s10552-009-9388-x