The results of electrophysiological tests in unilateral extensive peripapillary myelinated nerve fibers: report of three cases

The purpose of this study is to describe clinical and electrophysiological findings of three patients with unilateral extensive peripapillary myelinated nerve fibers. Three patients with unilateral extensive peripapillary myelinated nerve fibers were examined. A complete ophthalmologic examination i...

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Bibliographic Details
Published in:Documenta ophthalmologica 2009-12, Vol.119 (3), p.225-228
Main Authors: Arda, Hatice, Oner, Ayse, Gumus, Koray, Karakucuk, Sarper, Mirza, Ertugrul
Format: Article
Language:English
Subjects:
Adolescent
Biological and medical sciences
Case Report
Electroretinography
Evoked Potentials, Visual
Female
Fluorescein Angiography
Fundus Oculi
Humans
Male
Medical sciences
Medicine
Medicine & Public Health
Nerve Fibers, Myelinated - pathology
Nerve Fibers, Myelinated - physiology
Ophthalmology
Ophthalmoscopy
Retina - pathology
Retina - physiopathology
Tomography, Optical Coherence
Vision Disorders - etiology
Vision Disorders - pathology
Vision Disorders - physiopathology
Visual Acuity
Visual Field Tests
Visual Fields
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Summary:The purpose of this study is to describe clinical and electrophysiological findings of three patients with unilateral extensive peripapillary myelinated nerve fibers. Three patients with unilateral extensive peripapillary myelinated nerve fibers were examined. A complete ophthalmologic examination including uncorrected and best spectacle corrected visual acuities (UCVA, BSCVA) on Snellen charts, dilated fundoscopy, fundus fluorescein angiography (FFA), optical coherence tomography (OCT), perimetry and electrophysiological tests was performed. ERG results of both eyes were normal in all cases. FFA showed hypofluorescence at the myelinated nerve fibers (MNF) area in the affected eyes. We found a visual field defect resembling arcuat scotom at perimetry of the affected eyes. In OCT, there was hyper-reflectivity in reply to MNF. In all cases, pattern ERG results of the affected eyes showed decreased amplitudes and increased latencies of P50 and N95 waves. P100 amplitudes of PVER and FVER were decreased, and latencies were increased in all affected eyes. Extensive peripapillary myelinated nerve fibers may cause changes in PERG and VER.
ISSN:0012-4486
1573-2622
DOI:10.1007/s10633-009-9199-0