Intraspinal primitive neuroectodermal tumors: Report of four cases and review of the literature

Intraspinal primitive neuroectodermal tumors (PNETs) are extremely rare and are aggressive with poor outcomes. Till date only 41 cases of intraspinal PNET have been reported. Here we report four new cases. Total excision of the tumor was done in three patients and partial excision in one patient. Th...

Full description

Saved in:
Bibliographic Details
Published in:Neurology India 2009-09, Vol.57 (5), p.661-668
Main Authors: Jingyu, Chen, Jinning, Song, Hui, Meng, Hua, Feng
Format: Article
Language:English
Subjects:
Brain - pathology
Cancer
Case studies
Chemotherapy
Excision (Surgery)
Female
Health aspects
Humans
Magnetic Resonance Imaging - methods
Male
Middle Aged
Neuroectodermal Tumors, Primitive - diagnosis
Neuroectodermal Tumors, Primitive - metabolism
Phosphopyruvate Hydratase - metabolism
Radiotherapy
Spinal Cord - metabolism
Spinal Cord - pathology
Spinal Neoplasms - diagnosis
Spinal Neoplasms - metabolism
Young Adult
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Intraspinal primitive neuroectodermal tumors (PNETs) are extremely rare and are aggressive with poor outcomes. Till date only 41 cases of intraspinal PNET have been reported. Here we report four new cases. Total excision of the tumor was done in three patients and partial excision in one patient. The unusual clinical features were vertebral metasis in one patient and short history of symptoms for four days. All had surgical excision, total excision in three patients and gross partial excision in one patient. Three patients were treated with craniospinal radiotherapy and chemotherapy. All the four patients are alive and asymptomatic at 6 to 25 months of followup.
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.57804