Detection of bone erosion in early rheumatoid arthritis: ultrasonography and conventional radiography versus non-contrast magnetic resonance imaging

Nowadays, there is a trend toward early diagnosis and treatment of rheumatoid arthritis (RA) especially in patients with early signs of bone erosion which can be detected by magnetic resonance imaging (MRI). The aim of following study is to compare the sensitivity and specificity of ultrasonography...

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Bibliographic Details
Published in:Clinical rheumatology 2010-08, Vol.29 (8), p.883-891
Main Authors: Rahmani, Maryam, Chegini, Hosein, Najafizadeh, Seyed Reza, Azimi, Mohammad, Habibollahi, Peiman, Shakiba, Madjid
Format: Article
Language:English
Subjects:
Adult
Aged
Arthritis, Rheumatoid - diagnostic imaging
Arthritis, Rheumatoid - pathology
Bone and Bones - diagnostic imaging
Bone and Bones - pathology
Bone erosion
Bone Resorption - diagnostic imaging
Bone Resorption - pathology
Female
Humans
Magnetic Resonance Imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Original Article
Radiography
Reproducibility of Results
rheumatoid arthritis
Rheumatology
Sensitivity and Specificity
Severity of Illness Index
Ultrasonography
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Summary:Nowadays, there is a trend toward early diagnosis and treatment of rheumatoid arthritis (RA) especially in patients with early signs of bone erosion which can be detected by magnetic resonance imaging (MRI). The aim of following study is to compare the sensitivity and specificity of ultrasonography (US) and conventional radiography (CR) compared to MRI for early detection of bone erosion in RA patients. In 12 patients with RA diagnosis, 120 first to fifth metacarpophalangeal joints and 96 second to fifth proximal interphalangeal joints were examined. Non-contrast MRI, US and CR were performed for bone erosion evaluation. For further analysis, the patients were divided in two equal groups according to disease activity score (DAS28). The overall sensitivity and specificity of US compared to MRI in detecting bone erosion were 0.63 and 0.98, respectively with a considerable agreement (kappa = 0.68, p 
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-010-1423-5