Effect of a Standardized Radiation Dose Reduction Protocol on Diagnostic Accuracy of Coronary Computed Tomographic Angiography

Although numerous strategies for radiation dose decrease in coronary computed tomographic angiography are effective, their combined impact on diagnostic performance is not known. We therefore assessed the effect of a standardized coronary computed tomographic angiographic protocol on diagnostic accu...

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Bibliographic Details
Published in:The American journal of cardiology 2010-07, Vol.106 (2), p.287-292
Main Authors: LaBounty, Troy M., MD, Leipsic, Jonathon, MD, Mancini, G.B. John, MD, Heilbron, Brett, MD, Patel, Smita, MD, Kazerooni, Ella A., MD, MS, Sundaram, Baskaran, MBBS, Lin, Fay Y., MD, MS, Dunning, Allison, MS, Saltzman, Adam J., MD, Weisz, Giora, MD, Weinsaft, Jonathan W., MD, Choi, Jin-Ho, MD, Koduru, Sunaina, MD, Min, James K., MD
Format: Article
Language:English
Subjects:
Adult
Aged
Applied radiobiology (equipment, dosimetry...)
Biological and medical sciences
Biological effects of radiation
Cardiology
Cardiology. Vascular system
Cardiovascular
Cardiovascular system
Clinical medicine
Coronary Angiography - methods
Coronary Artery Disease - diagnostic imaging
Female
Fundamental and applied biological sciences. Psychology
Heart
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical imaging
Medical sciences
Middle Aged
Radiation Dosage
Radiation therapy
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Tissues, organs and organisms biophysics
Tomography
Tomography, X-Ray Computed - methods
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Summary:Although numerous strategies for radiation dose decrease in coronary computed tomographic angiography are effective, their combined impact on diagnostic performance is not known. We therefore assessed the effect of a standardized coronary computed tomographic angiographic protocol on diagnostic accuracy. We evaluated 80 consecutive patients from 3 sites with coronary computed tomographic angiography and quantitative coronary angiography. All sites initially used nonstandardized protocols; 2 sites then initiated a standardized protocol, and 1 site continued its nonstandardized protocol as a time-overlapping control. Two blinded readers interpreted coronary computed tomographic angiographic studies; a third obtained consensus. A blinded core laboratory performed quantitative coronary angiography. Each segment was graded as
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2010.02.038