Successful treatment of periodontal mucormycosis: report of a case and literature review

Mucormycosis is an aggressive and potentially devastating fungal infection which typically manifests in pulmonary, rhinocerebral, or disseminated forms in patients with hematologic malignancy. Mucormycosis confined to the periodontium is uncommon, and to our knowledge only 6 cases have been reported...

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Published in:Oral surgery, oral medicine, oral pathology, oral radiology and endodontics oral medicine, oral pathology, oral radiology and endodontics, 2010-03, Vol.109 (3), p.e64-e69
Main Authors: McDermott, Nancy E., DMD, MD, Barrett, John, MD, Hipp, Jason, MD, PhD, Merino, Maria J., MD, Richard Lee, Chyi-Chia, MD, PhD, Waterman, Paige, MD, Domingo, Demetrio L., DDS, MS, Walsh, Thomas J., MD
Format: Article
Language:English
Subjects:
Acute Disease
Debridement - methods
Dentistry
Female
Hematopoietic Stem Cell Transplantation
Humans
Immunocompromised Host
Indexing in process
Leukemia, Myeloid, Acute - complications
Leukemia, Myeloid, Acute - therapy
Middle Aged
Mucormycosis - complications
Mucormycosis - therapy
Periodontal Diseases - etiology
Periodontal Diseases - microbiology
Periodontal Diseases - therapy
Periodontium - microbiology
Periodontium - pathology
Periodontium - surgery
Surgery
Transplantation Conditioning - adverse effects
Treatment Outcome
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Description
Summary:Mucormycosis is an aggressive and potentially devastating fungal infection which typically manifests in pulmonary, rhinocerebral, or disseminated forms in patients with hematologic malignancy. Mucormycosis confined to the periodontium is uncommon, and to our knowledge only 6 cases have been reported in the English-language literature. This case report describes a patient with acute leukemia and periodontal mucormycosis. Calcofluor fluorescence microscopy is also proposed as a method for establishing a prompt diagnosis and guiding extent of intraoperative surgical debridement.
ISSN:1079-2104
1528-395X
DOI:10.1016/j.tripleo.2009.11.012