Cytomegalovirus Retinitis Associated with Good's Syndrome

Purpose. To report a case of cytomegalovirus (CMV) retinitis associated with Good's syndrome. Methods. A 57-year-old man presented to our ophthalmology clinic with complaints of visual loss in the left eye for 2 weeks. His medical anamnesis revealed myasthenia gravis, thymoma resection, multipl...

Full description

Saved in:
Bibliographic Details
Published in:European journal of ophthalmology 2010-03, Vol.20 (2), p.479-480
Main Authors: Mateo-Montoya, Aranzazu, Stanescu, Dinu, Wolff, Benjamin, Sahel, José-Alain, Bonnel, Sébastien
Format: Article
Language:English
Subjects:
Acyclovir - administration & dosage
Agammaglobulinemia - complications
Antiviral Agents - administration & dosage
Aqueous Humor - virology
Cytomegalovirus - genetics
Cytomegalovirus - isolation & purification
Cytomegalovirus Retinitis - complications
Cytomegalovirus Retinitis - diagnosis
Cytomegalovirus Retinitis - drug therapy
Diagnosis, Differential
DNA, Viral - genetics
Drug Therapy, Combination
Fluorescein Angiography
Follow-Up Studies
Fundus Oculi
Ganciclovir - administration & dosage
Humans
Injections
Male
Middle Aged
Polymerase Chain Reaction
Syndrome
Thymoma - complications
Thymus Neoplasms - complications
Visual Acuity
Vitreous Body
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose. To report a case of cytomegalovirus (CMV) retinitis associated with Good's syndrome. Methods. A 57-year-old man presented to our ophthalmology clinic with complaints of visual loss in the left eye for 2 weeks. His medical anamnesis revealed myasthenia gravis, thymoma resection, multiple chest infections, and Campylobacter septicemia. Left eye examination revealed mild anterior uveitis, moderate vitritis, and superotemporal active retinitis. Results. Polymerase chain reaction of both aqueous humor and vitreous tap were positive for CMV DNA, which suggested CMV retinitis. The patient was treated with systemic treatment of acyclovir and ganciclovir combined with weekly intravitreal injections of ganciclovir and foscarnet. Retinitis resolved within 3 weeks and visual acuity improved. Conclusions. CMV retinitis can be associated with Good's syndrome.
ISSN:1120-6721
1724-6016
DOI:10.1177/112067211002000238