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Cytomegalovirus Retinitis Associated with Good's Syndrome
Purpose. To report a case of cytomegalovirus (CMV) retinitis associated with Good's syndrome. Methods. A 57-year-old man presented to our ophthalmology clinic with complaints of visual loss in the left eye for 2 weeks. His medical anamnesis revealed myasthenia gravis, thymoma resection, multipl...
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| Published in: | European journal of ophthalmology 2010-03, Vol.20 (2), p.479-480 |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c342t-6099128eda22828dcf89401360b359e2edb1f19e6390fe549b373b3dd8aa4373 |
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| cites | cdi_FETCH-LOGICAL-c342t-6099128eda22828dcf89401360b359e2edb1f19e6390fe549b373b3dd8aa4373 |
| container_end_page | 480 |
| container_issue | 2 |
| container_start_page | 479 |
| container_title | European journal of ophthalmology |
| container_volume | 20 |
| creator | Mateo-Montoya, Aranzazu Stanescu, Dinu Wolff, Benjamin Sahel, José-Alain Bonnel, Sébastien |
| description | Purpose.
To report a case of cytomegalovirus (CMV) retinitis associated with Good's syndrome.
Methods.
A 57-year-old man presented to our ophthalmology clinic with complaints of visual loss in the left eye for 2 weeks. His medical anamnesis revealed myasthenia gravis, thymoma resection, multiple chest infections, and Campylobacter septicemia. Left eye examination revealed mild anterior uveitis, moderate vitritis, and superotemporal active retinitis.
Results.
Polymerase chain reaction of both aqueous humor and vitreous tap were positive for CMV DNA, which suggested CMV retinitis. The patient was treated with systemic treatment of acyclovir and ganciclovir combined with weekly intravitreal injections of ganciclovir and foscarnet. Retinitis resolved within 3 weeks and visual acuity improved.
Conclusions.
CMV retinitis can be associated with Good's syndrome. |
| doi_str_mv | 10.1177/112067211002000238 |
| format | article |
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To report a case of cytomegalovirus (CMV) retinitis associated with Good's syndrome.
Methods.
A 57-year-old man presented to our ophthalmology clinic with complaints of visual loss in the left eye for 2 weeks. His medical anamnesis revealed myasthenia gravis, thymoma resection, multiple chest infections, and Campylobacter septicemia. Left eye examination revealed mild anterior uveitis, moderate vitritis, and superotemporal active retinitis.
Results.
Polymerase chain reaction of both aqueous humor and vitreous tap were positive for CMV DNA, which suggested CMV retinitis. The patient was treated with systemic treatment of acyclovir and ganciclovir combined with weekly intravitreal injections of ganciclovir and foscarnet. Retinitis resolved within 3 weeks and visual acuity improved.
Conclusions.
CMV retinitis can be associated with Good's syndrome.</description><identifier>ISSN: 1120-6721</identifier><identifier>EISSN: 1724-6016</identifier><identifier>DOI: 10.1177/112067211002000238</identifier><identifier>PMID: 19882506</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Acyclovir - administration & dosage ; Agammaglobulinemia - complications ; Antiviral Agents - administration & dosage ; Aqueous Humor - virology ; Cytomegalovirus - genetics ; Cytomegalovirus - isolation & purification ; Cytomegalovirus Retinitis - complications ; Cytomegalovirus Retinitis - diagnosis ; Cytomegalovirus Retinitis - drug therapy ; Diagnosis, Differential ; DNA, Viral - genetics ; Drug Therapy, Combination ; Fluorescein Angiography ; Follow-Up Studies ; Fundus Oculi ; Ganciclovir - administration & dosage ; Humans ; Injections ; Male ; Middle Aged ; Polymerase Chain Reaction ; Syndrome ; Thymoma - complications ; Thymus Neoplasms - complications ; Visual Acuity ; Vitreous Body</subject><ispartof>European journal of ophthalmology, 2010-03, Vol.20 (2), p.479-480</ispartof><rights>2010 SAGE Publications</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c342t-6099128eda22828dcf89401360b359e2edb1f19e6390fe549b373b3dd8aa4373</citedby><cites>FETCH-LOGICAL-c342t-6099128eda22828dcf89401360b359e2edb1f19e6390fe549b373b3dd8aa4373</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925,79364</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19882506$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mateo-Montoya, Aranzazu</creatorcontrib><creatorcontrib>Stanescu, Dinu</creatorcontrib><creatorcontrib>Wolff, Benjamin</creatorcontrib><creatorcontrib>Sahel, José-Alain</creatorcontrib><creatorcontrib>Bonnel, Sébastien</creatorcontrib><title>Cytomegalovirus Retinitis Associated with Good's Syndrome</title><title>European journal of ophthalmology</title><addtitle>Eur J Ophthalmol</addtitle><description>Purpose.
To report a case of cytomegalovirus (CMV) retinitis associated with Good's syndrome.
Methods.
A 57-year-old man presented to our ophthalmology clinic with complaints of visual loss in the left eye for 2 weeks. His medical anamnesis revealed myasthenia gravis, thymoma resection, multiple chest infections, and Campylobacter septicemia. Left eye examination revealed mild anterior uveitis, moderate vitritis, and superotemporal active retinitis.
Results.
Polymerase chain reaction of both aqueous humor and vitreous tap were positive for CMV DNA, which suggested CMV retinitis. The patient was treated with systemic treatment of acyclovir and ganciclovir combined with weekly intravitreal injections of ganciclovir and foscarnet. Retinitis resolved within 3 weeks and visual acuity improved.
Conclusions.
CMV retinitis can be associated with Good's syndrome.</description><subject>Acyclovir - administration & dosage</subject><subject>Agammaglobulinemia - complications</subject><subject>Antiviral Agents - administration & dosage</subject><subject>Aqueous Humor - virology</subject><subject>Cytomegalovirus - genetics</subject><subject>Cytomegalovirus - isolation & purification</subject><subject>Cytomegalovirus Retinitis - complications</subject><subject>Cytomegalovirus Retinitis - diagnosis</subject><subject>Cytomegalovirus Retinitis - drug therapy</subject><subject>Diagnosis, Differential</subject><subject>DNA, Viral - genetics</subject><subject>Drug Therapy, Combination</subject><subject>Fluorescein Angiography</subject><subject>Follow-Up Studies</subject><subject>Fundus Oculi</subject><subject>Ganciclovir - administration & dosage</subject><subject>Humans</subject><subject>Injections</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Polymerase Chain Reaction</subject><subject>Syndrome</subject><subject>Thymoma - complications</subject><subject>Thymus Neoplasms - complications</subject><subject>Visual Acuity</subject><subject>Vitreous Body</subject><issn>1120-6721</issn><issn>1724-6016</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNp9kE9Lw0AQxRdRbK1-AQ-SW0-x-y-b3WMpWoWCoL2HTXZStyTZupso_fbd0oIHwcMw7_B7j5mH0D3Bj4Tk-YwQikVOCcGY4jhMXqAxySlPBSbiMuoIpEdihG5C2B4xxek1GhElJc2wGCO12PeuhY1u3Lf1Q0jeobed7W1I5iG4yuoeTPJj-89k6ZyZhuRj3xkfLbfoqtZNgLvznqD189N68ZKu3pavi_kqrRinfTxFKUIlGE2ppNJUtVQcEyZwyTIFFExJaqJAMIVryLgqWc5KZozUmkc5QdNT7M67rwFCX7Q2VNA0ugM3hCJnTHCORRZJeiIr70LwUBc7b1vt9wXBxbGw4m9h0fRwjh_KFsyv5dxQBGYnIOgNFFs3-C5--1_kAVfHcZs</recordid><startdate>20100301</startdate><enddate>20100301</enddate><creator>Mateo-Montoya, Aranzazu</creator><creator>Stanescu, Dinu</creator><creator>Wolff, Benjamin</creator><creator>Sahel, José-Alain</creator><creator>Bonnel, Sébastien</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100301</creationdate><title>Cytomegalovirus Retinitis Associated with Good's Syndrome</title><author>Mateo-Montoya, Aranzazu ; Stanescu, Dinu ; Wolff, Benjamin ; Sahel, José-Alain ; Bonnel, Sébastien</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c342t-6099128eda22828dcf89401360b359e2edb1f19e6390fe549b373b3dd8aa4373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Acyclovir - administration & dosage</topic><topic>Agammaglobulinemia - complications</topic><topic>Antiviral Agents - administration & dosage</topic><topic>Aqueous Humor - virology</topic><topic>Cytomegalovirus - genetics</topic><topic>Cytomegalovirus - isolation & purification</topic><topic>Cytomegalovirus Retinitis - complications</topic><topic>Cytomegalovirus Retinitis - diagnosis</topic><topic>Cytomegalovirus Retinitis - drug therapy</topic><topic>Diagnosis, Differential</topic><topic>DNA, Viral - genetics</topic><topic>Drug Therapy, Combination</topic><topic>Fluorescein Angiography</topic><topic>Follow-Up Studies</topic><topic>Fundus Oculi</topic><topic>Ganciclovir - administration & dosage</topic><topic>Humans</topic><topic>Injections</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Polymerase Chain Reaction</topic><topic>Syndrome</topic><topic>Thymoma - complications</topic><topic>Thymus Neoplasms - complications</topic><topic>Visual Acuity</topic><topic>Vitreous Body</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mateo-Montoya, Aranzazu</creatorcontrib><creatorcontrib>Stanescu, Dinu</creatorcontrib><creatorcontrib>Wolff, Benjamin</creatorcontrib><creatorcontrib>Sahel, José-Alain</creatorcontrib><creatorcontrib>Bonnel, Sébastien</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mateo-Montoya, Aranzazu</au><au>Stanescu, Dinu</au><au>Wolff, Benjamin</au><au>Sahel, José-Alain</au><au>Bonnel, Sébastien</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cytomegalovirus Retinitis Associated with Good's Syndrome</atitle><jtitle>European journal of ophthalmology</jtitle><addtitle>Eur J Ophthalmol</addtitle><date>2010-03-01</date><risdate>2010</risdate><volume>20</volume><issue>2</issue><spage>479</spage><epage>480</epage><pages>479-480</pages><issn>1120-6721</issn><eissn>1724-6016</eissn><abstract>Purpose.
To report a case of cytomegalovirus (CMV) retinitis associated with Good's syndrome.
Methods.
A 57-year-old man presented to our ophthalmology clinic with complaints of visual loss in the left eye for 2 weeks. His medical anamnesis revealed myasthenia gravis, thymoma resection, multiple chest infections, and Campylobacter septicemia. Left eye examination revealed mild anterior uveitis, moderate vitritis, and superotemporal active retinitis.
Results.
Polymerase chain reaction of both aqueous humor and vitreous tap were positive for CMV DNA, which suggested CMV retinitis. The patient was treated with systemic treatment of acyclovir and ganciclovir combined with weekly intravitreal injections of ganciclovir and foscarnet. Retinitis resolved within 3 weeks and visual acuity improved.
Conclusions.
CMV retinitis can be associated with Good's syndrome.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>19882506</pmid><doi>10.1177/112067211002000238</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1120-6721 |
| ispartof | European journal of ophthalmology, 2010-03, Vol.20 (2), p.479-480 |
| issn | 1120-6721 1724-6016 |
| language | eng |
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| source | SAGE |
| subjects | Acyclovir - administration & dosage Agammaglobulinemia - complications Antiviral Agents - administration & dosage Aqueous Humor - virology Cytomegalovirus - genetics Cytomegalovirus - isolation & purification Cytomegalovirus Retinitis - complications Cytomegalovirus Retinitis - diagnosis Cytomegalovirus Retinitis - drug therapy Diagnosis, Differential DNA, Viral - genetics Drug Therapy, Combination Fluorescein Angiography Follow-Up Studies Fundus Oculi Ganciclovir - administration & dosage Humans Injections Male Middle Aged Polymerase Chain Reaction Syndrome Thymoma - complications Thymus Neoplasms - complications Visual Acuity Vitreous Body |
| title | Cytomegalovirus Retinitis Associated with Good's Syndrome |
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