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Systematic review: the role of self‐expanding plastic stents for benign oesophageal strictures

Aliment Pharmacol Ther 31, 1268–1275 Summary Background  Treatment of refractory or recurrent benign oesophageal strictures is demanding and surgery may be the only available option. The role of self‐expanding plastic stents (SEPS) in the treatment of these strictures is still controversial because...

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Published in:Alimentary pharmacology & therapeutics 2010-06, Vol.31 (12), p.1268-1275
Main Authors: REPICI, A., HASSAN, C., SHARMA, P., CONIO, M., SIERSEMA, P.
Format: Article
Language:English
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Summary:Aliment Pharmacol Ther 31, 1268–1275 Summary Background  Treatment of refractory or recurrent benign oesophageal strictures is demanding and surgery may be the only available option. The role of self‐expanding plastic stents (SEPS) in the treatment of these strictures is still controversial because of the conflicting results of various studies. Aim  To analyse with regard to SEPS: technical and clinical success, factors associated with outcome, and safety. Methods  Pooled‐data analysis of a systematic review of the literature. Clinical success was defined as no need for further endoscopic or surgical treatment after SEPS removal. Results  Data of 10 studies with 130 treated patients were included. SEPS insertion was technically successful in 128 of 130 patients (98%, 95% CI = 96–100%). Clinical success was achieved in 68 patients (52%, 95% CI = 44–61%) and this was found to be lower in those with a cervical localization of the stricture (33% vs. 54%; P 
ISSN:0269-2813
1365-2036
DOI:10.1111/j.1365-2036.2010.04301.x