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Allergic skin diseases
The skin is one of the largest immunologic organs and is affected by both external and internal factors, as well as innate and adaptive immune responses. Many skin disorders, such as atopic dermatitis, contact dermatitis, urticaria, angioedema, psoriasis, and autoimmune blistering disorders, are imm...
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Published in: | Journal of allergy and clinical immunology 2010-02, Vol.125 (2), p.S138-S149 |
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container_end_page | S149 |
container_issue | 2 |
container_start_page | S138 |
container_title | Journal of allergy and clinical immunology |
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creator | Fonacier, Luz S., MD Dreskin, Stephen C., MD, PhD Leung, Donald Y.M., MD, PhD |
description | The skin is one of the largest immunologic organs and is affected by both external and internal factors, as well as innate and adaptive immune responses. Many skin disorders, such as atopic dermatitis, contact dermatitis, urticaria, angioedema, psoriasis, and autoimmune blistering disorders, are immune mediated. Most of these diseases are chronic, inflammatory, and proliferative, in which both genetic and environmental factors play important roles. These immunologic mechanisms might have implications for potential targets of future therapeutic interventions. |
doi_str_mv | 10.1016/j.jaci.2009.05.039 |
format | article |
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Many skin disorders, such as atopic dermatitis, contact dermatitis, urticaria, angioedema, psoriasis, and autoimmune blistering disorders, are immune mediated. Most of these diseases are chronic, inflammatory, and proliferative, in which both genetic and environmental factors play important roles. 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Many skin disorders, such as atopic dermatitis, contact dermatitis, urticaria, angioedema, psoriasis, and autoimmune blistering disorders, are immune mediated. Most of these diseases are chronic, inflammatory, and proliferative, in which both genetic and environmental factors play important roles. These immunologic mechanisms might have implications for potential targets of future therapeutic interventions.</description><subject>Adaptive Immunity</subject><subject>Allergens - immunology</subject><subject>Allergic contact dermatitis</subject><subject>Allergies</subject><subject>Allergy and Immunology</subject><subject>atopic dermatitis</subject><subject>autoimmune blistering disease</subject><subject>Dermatitis</subject><subject>Dermatitis, Allergic Contact - diagnosis</subject><subject>Dermatitis, Allergic Contact - immunology</subject><subject>Dermatitis, Allergic Contact - physiopathology</subject><subject>Dermatitis, Allergic Contact - therapy</subject><subject>Dermatitis, Atopic - genetics</subject><subject>Dermatitis, Atopic - immunology</subject><subject>Dermatitis, Atopic - therapy</subject><subject>Eczema</subject><subject>Environmental Exposure</subject><subject>Genetic Predisposition to Disease</subject><subject>Humans</subject><subject>Immune system</subject><subject>immune-mediated skin disorders</subject><subject>Immunity, Innate</subject><subject>Immunotherapy - trends</subject><subject>irritant contact dermatitis</subject><subject>Lymphocytes</subject><subject>Pemphigus - immunology</subject><subject>Pemphigus - physiopathology</subject><subject>Pemphigus - therapy</subject><subject>psoriasis</subject><subject>Psoriasis - diagnosis</subject><subject>Psoriasis - immunology</subject><subject>Psoriasis - physiopathology</subject><subject>Psoriasis - therapy</subject><subject>Skin diseases</subject><subject>Urticaria</subject><issn>0091-6749</issn><issn>1097-6825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNp9kUtLxDAURoMozvjYunAhggtXrTdJ8wIRRHzBgAt1HTLpraR2Wk1mBP-9KTMguHAVwj3fR3IuIccUSgpUXrRl63woGYApQZTAzRaZUjCqkJqJbTLNA1pIVZkJ2UuphXzn2uySCTWGM8PolBxddx3Gt-BP03voT-uQ0CVMB2SncV3Cw825T17vbl9uHorZ0_3jzfWs8JXky4J7zaiee-U8x0bpqhJeKMFq3ThArtnczWVdc9YwpxA5Gp7HRnhtjK4d5fvkfN37EYfPFaalXYTksetcj8MqWcW5lMCozOTZH7IdVrHPj7NUQKWVUXqk2JrycUgpYmM_Yli4-G0p2FGabe0ozY7SLAibpeXQyaZ6NV9g_RvZWMrA5RrArOIrYLTJB-w91iGiX9p6CP_3X_2J-y70wbvuHb8x_f7DJmbBPo9rG7cGBkBLwfkP0NWPYg</recordid><startdate>20100201</startdate><enddate>20100201</enddate><creator>Fonacier, Luz S., MD</creator><creator>Dreskin, Stephen C., MD, PhD</creator><creator>Leung, Donald Y.M., MD, PhD</creator><general>Mosby, Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20100201</creationdate><title>Allergic skin diseases</title><author>Fonacier, Luz S., MD ; Dreskin, Stephen C., MD, PhD ; Leung, Donald Y.M., MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c463t-3c8218bc7ac3ef78445c5752d8fa0e382bab6dd32f2a7ee3e9357595c8998da13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adaptive Immunity</topic><topic>Allergens - immunology</topic><topic>Allergic contact dermatitis</topic><topic>Allergies</topic><topic>Allergy and Immunology</topic><topic>atopic dermatitis</topic><topic>autoimmune blistering disease</topic><topic>Dermatitis</topic><topic>Dermatitis, Allergic Contact - diagnosis</topic><topic>Dermatitis, Allergic Contact - immunology</topic><topic>Dermatitis, Allergic Contact - physiopathology</topic><topic>Dermatitis, Allergic Contact - therapy</topic><topic>Dermatitis, Atopic - genetics</topic><topic>Dermatitis, Atopic - immunology</topic><topic>Dermatitis, Atopic - therapy</topic><topic>Eczema</topic><topic>Environmental Exposure</topic><topic>Genetic Predisposition to Disease</topic><topic>Humans</topic><topic>Immune system</topic><topic>immune-mediated skin disorders</topic><topic>Immunity, Innate</topic><topic>Immunotherapy - trends</topic><topic>irritant contact dermatitis</topic><topic>Lymphocytes</topic><topic>Pemphigus - immunology</topic><topic>Pemphigus - physiopathology</topic><topic>Pemphigus - therapy</topic><topic>psoriasis</topic><topic>Psoriasis - diagnosis</topic><topic>Psoriasis - immunology</topic><topic>Psoriasis - physiopathology</topic><topic>Psoriasis - therapy</topic><topic>Skin diseases</topic><topic>Urticaria</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fonacier, Luz S., MD</creatorcontrib><creatorcontrib>Dreskin, Stephen C., MD, PhD</creatorcontrib><creatorcontrib>Leung, Donald Y.M., MD, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of allergy and clinical immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fonacier, Luz S., MD</au><au>Dreskin, Stephen C., MD, PhD</au><au>Leung, Donald Y.M., MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Allergic skin diseases</atitle><jtitle>Journal of allergy and clinical immunology</jtitle><addtitle>J Allergy Clin Immunol</addtitle><date>2010-02-01</date><risdate>2010</risdate><volume>125</volume><issue>2</issue><spage>S138</spage><epage>S149</epage><pages>S138-S149</pages><issn>0091-6749</issn><eissn>1097-6825</eissn><abstract>The skin is one of the largest immunologic organs and is affected by both external and internal factors, as well as innate and adaptive immune responses. 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subjects | Adaptive Immunity Allergens - immunology Allergic contact dermatitis Allergies Allergy and Immunology atopic dermatitis autoimmune blistering disease Dermatitis Dermatitis, Allergic Contact - diagnosis Dermatitis, Allergic Contact - immunology Dermatitis, Allergic Contact - physiopathology Dermatitis, Allergic Contact - therapy Dermatitis, Atopic - genetics Dermatitis, Atopic - immunology Dermatitis, Atopic - therapy Eczema Environmental Exposure Genetic Predisposition to Disease Humans Immune system immune-mediated skin disorders Immunity, Innate Immunotherapy - trends irritant contact dermatitis Lymphocytes Pemphigus - immunology Pemphigus - physiopathology Pemphigus - therapy psoriasis Psoriasis - diagnosis Psoriasis - immunology Psoriasis - physiopathology Psoriasis - therapy Skin diseases Urticaria |
title | Allergic skin diseases |
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