Insulin-Like Growth Factor I Signaling in Skeletal Muscle and the Potential for Cytokine Interactions

Recent research has demonstrated that intracellular signaling components associated with several proinflammatory cytokines have the potential to interact with signaling pathways that regulate anabolic processes in skeletal muscle. This presentation and the ensuing brief review are intended to presen...

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Bibliographic Details
Published in:Medicine and science in sports and exercise 2010, Vol.42 (1), p.50-57
Main Author: ADAMS, Gregory R
Format: Article
Language:English
Subjects:
Adaptation, Physiological
Animals
Biological and medical sciences
Cytokines - metabolism
Extracellular Signal-Regulated MAP Kinases - metabolism
Fundamental and applied biological sciences. Psychology
Humans
Insulin-Like Growth Factor I - metabolism
Intracellular Signaling Peptides and Proteins - metabolism
Muscle, Skeletal - growth & development
Muscle, Skeletal - metabolism
Protein-Serine-Threonine Kinases - metabolism
Receptor Cross-Talk - physiology
Signal Transduction - physiology
Space life sciences
TOR Serine-Threonine Kinases
Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports
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Summary:Recent research has demonstrated that intracellular signaling components associated with several proinflammatory cytokines have the potential to interact with signaling pathways that regulate anabolic processes in skeletal muscle. This presentation and the ensuing brief review are intended to present a selection of the potential interactions between these two critical processes.
ISSN:0195-9131
1530-0315
DOI:10.1249/MSS.0b013e3181b07d12