Biosynthetic maturation of the corpus allatum of the female adult medfly, Ceratitis capitata, and its putative control

The major juvenile hormone (JH) homolog synthesized in vitro by the adult female Medfly (Ceratitis capitata) corpus allatum (CA) is JHB3, with JH-III the minor homolog. Methyl-incorporation in vitro in post-eclosion virgin females is age-dependent. Basal activity occurs during the first four days po...

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Bibliographic Details
Published in:Journal of insect physiology 2003-06, Vol.49 (6), p.603-609
Main Authors: Moshitzky, P., Gilbert, L.I., Applebaum, S.W.
Format: Article
Language:English
Subjects:
Aging - physiology
Animals
Ceratitis capitata
Ceratitis capitata - drug effects
Ceratitis capitata - growth & development
Ceratitis capitata - metabolism
Corpora Allata - drug effects
Corpora Allata - growth & development
Corpora Allata - metabolism
Drosophila Proteins
Fatty Acids, Unsaturated - pharmacology
Female
Juvenile hormone
Juvenile Hormones - biosynthesis
Lovastatin - pharmacology
Ovarian maturation
Peptides - pharmacology
Sex peptide
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Summary:The major juvenile hormone (JH) homolog synthesized in vitro by the adult female Medfly (Ceratitis capitata) corpus allatum (CA) is JHB3, with JH-III the minor homolog. Methyl-incorporation in vitro in post-eclosion virgin females is age-dependent. Basal activity occurs during the first four days post-eclosion and increases significantly thereafter, peaking at five days. Biosynthetic maturation of the mated female CA is delayed by one day and reduced considerably. The delayed response may be due to direct cerebral or neural inhibition. Synthetic Drosophila melanogaster sex peptide depresses JH biosynthesis by the Medfly female CA in vitro. Male-derived accessory gland peptides of the Medfly are transferred to the female during mating and a Medfly SP-analog may be responsible for down-regulation of JH synthesis by the CA in mated Medfly females. Mevinolin, an inhibitor of the mevalonate pathway, significantly reduces the biosynthesis of JHB3, while farnesoic acid, a proximate precursor of JHIII, significantly stimulates the biosynthesis of both JHB3 and JHIII in vitro.
ISSN:0022-1910
1879-1611
DOI:10.1016/S0022-1910(03)00047-7