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A comparative study of fluctuating asymmetry in Chinese families with nonsyndromic cleft palate

OBJECTIVETo compare the asymmetry displayed by Chinese patients with nonsyndromic cleft palate (NSCP), their unaffected parents, and a control population.METHODWith rigorous inclusion criteria, a total number of 675 individuals with NSCP, 675 parental pairs of these patients, and 650 control individ...

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Bibliographic Details
Published in:The Cleft palate-craniofacial journal 2010-03, Vol.47 (2), p.182-188
Main Authors: Lu, Da-wei, Shi, Bing, Chen, Huai-qing, He, Xing, Liao, Li-shu, Zheng, Qian
Format: Article
Language:English
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Summary:OBJECTIVETo compare the asymmetry displayed by Chinese patients with nonsyndromic cleft palate (NSCP), their unaffected parents, and a control population.METHODWith rigorous inclusion criteria, a total number of 675 individuals with NSCP, 675 parental pairs of these patients, and 650 control individuals were involved in this case-control study. Size-adjusted fluctuating asymmetry (FA) scores were calculated by data on 10 variables. Analysis of variance was used for a three-way comparison of patients/gender-matched parents/gender-matched controls.RESULTSA significant increase in FA for ear length (p
ISSN:1545-1569
DOI:10.1597/08-197.1