Comparison of Local Anesthetic Effects of Tramadol With Prilocaine During Circumcision Procedure

• Published in: Urology (Ridgewood, N.J.) N.J.), 2010-03, Vol.75 (3), p.672-675
• Main Authors: Kargı, Eksal, Işıkdemir, Ahmet, Tokgöz, Hüsnü, Erol, Bülent, Işıkdemir, Fulden, Hancı, Volkan, Payaslı, Cem
• Format: Article
• Language: English
• Subjects: Analgesics, Opioid - therapeutic use; Anesthesia, Local; Anesthetics, Local - therapeutic use; Child; Circumcision, Male - adverse effects; Double-Blind Method; Drug Therapy, Combination; Humans; Male; Pain - etiology; Pain - prevention & control; Pain, Postoperative - prevention & control; Prilocaine - therapeutic use; Tramadol - therapeutic use; Urology
• ISSN: 0090-4295; 1527-9995
• DOI: 10.1016/j.urology.2009.06.108

Objectives To compare the local anesthetic effects of tramadol hydrochloride with prilocaine for circumcision procedure. Methods This study included 40 patients with American Surgical Association-I scores. Patients were randomly allocated to receive either 5% tramadol (2 mg/kg) plus adrenaline (0.0125/mL) (group 1, n = 20) or 2% prilocaine plus adrenaline (0.0125/mL) (group 2, n = 20). The degree of burning sensation and pain at the injection site were documented. Sensory block was assessed 1 minute after injection and the patients were asked to grade touch and pinprick sensation. Five minutes after drug administration, incision was performed and intensity of pain, felt by the patient was evaluated on a 4-point scale (0-3). Pain at the injection site and local skin reactions were also recorded. Results Mean ages were 9.7 and 10.3 years for groups 1 and 2, respectively. Mean duration of surgery was 19.6 minutes. In control visit, 2 of 20 (10%) in group 1 and 10 of 20 (50%) children in group 2 reported extra need for oral ibuprofen ( P .05). Total postoperative ibuprofen consumptions were 10 and 50 mg for groups 1 and 2, respectively ( P