THE EFFECT OF DIET ON THE HEMOGLOBIN, ERYTHROCYTE, AND LEUKOCYTE CONTENT OF THE BLOOD OF THE RHESUS MONKEY (MACACA MULATTA)

1. Rhesus monkeys fed purified rations supplemented with adequate amounts of the B vitamins, ascorbic acid, and whole liver substance maintained the following average blood picture: See PDF for Table 2. Natural diets or purified rations supplemented with liver extract do not support the above blood...

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Bibliographic Details
Published in:Blood 1947-03, Vol.2 (2), p.154-163
Main Authors: Jones, Edith Seymour, McCall, Keith B., Elvehjem, C.A., Clark, P.F.
Format: Article
Language:English
Subjects:
Animals
Blood - biosynthesis
Diet
Erythrocytes - biosynthesis
Hematopoietic System
Hemoglobins
Humans
Leukocytes
Macaca mulatta
Nutritional Sciences
Old Medline
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Summary:1. Rhesus monkeys fed purified rations supplemented with adequate amounts of the B vitamins, ascorbic acid, and whole liver substance maintained the following average blood picture: See PDF for Table 2. Natural diets or purified rations supplemented with liver extract do not support the above blood picture. The hemoglobin is lower and there is an increase in the range of the total leukocyte count and in the neutrophil-lymphocyte ratio to 2.0 ([unknown]). These figures are similar to the values in the literature and generally accepted as the normal. 3. Previous reports have shown the characteristic blood dyscrasias which develop when monkeys are fed certain B vitamin-deficient diets. These changes are summarized graphically in this paper. 4. The importance of determining the concentration of hemoglobin and the formed elements of the blood as a diagnostic test in nutritional studies has been shown.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V2.2.154.154