Simultaneous Screening and Target Analytical Approach by Gas Chromatography-Quadrupole-Mass Spectrometry for Pesticide Residues in Fruits and Vegetables

• Published in: Journal of AOAC International 2009-11, Vol.92 (6), p.1790-1806
• Main Authors: Mezcua, Milagros, Martínez-Uroz, Maria A, Wylie, Philip L, Fernández-Alba, Amadeo R
• Format: Article
• Language: English
• Subjects: Automation; Biological and medical sciences; Endocrine Disruptors - analysis; Food Analysis - methods; Food Analysis - standards; food contamination; Food industries; Fruit - chemistry; Fruit and vegetable industries; fruits (food); Fundamental and applied biological sciences. Psychology; Gas chromatography; Gas Chromatography-Mass Spectrometry; Identification and classification; Indicators and Reagents; Mass spectrometry; maximum residue limits; Olive Oil; Pesticide residues; Pesticide Residues - analysis; Plant Oils - analysis; quantitative analysis; screening; vegetables; Vegetables - chemistry
• ISSN: 1060-3271; 1944-7922
• DOI: 10.1093/jaoac/92.6.1790

A full-scan GC/quadrupole/MS method has been developed to perform large-scale screenings of pesticides and simultaneous quantification of 95 target compounds in a single run of 21 min. The screening method was performed by using a deconvolution of the spectrum of the full-scan data files acquired under a retention time locked method. The identification performance of the screening method was evaluated in eight different food matrixes at three different concentrations. The system was equipped with a programmable temperature vaporizing inlet, allowing 10 μL injections. The LOQ in the full-scan mode and linearity were studied for four different matrixes. Correlation coefficients >0.99 were achieved in all cases, and the LOD was