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Incomplete Kawasaki syndrome followed by systemic onset-juvenile idiopathic arthritis mimicking Kawasaki syndrome

A 3-month-old child was first treated for incomplete Kawasaki syndrome with three cycles of intravenous immunoglobulins and aspirin, then with methylprednisolone which led to fever remission. The same child was re-hospitalized after a 10-month-period of well-being for the suspicion of a new episode...

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Bibliographic Details
Published in:Rheumatology international 2010-02, Vol.30 (4), p.535-539
Main Authors: Rigante, Donato, Valentini, Piero, Onesimo, Roberta, Angelone, Donatella Francesca, De Nisco, Alessia, Bersani, Giulia, Delogu, Angelica Bibiana
Format: Article
Language:English
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Summary:A 3-month-old child was first treated for incomplete Kawasaki syndrome with three cycles of intravenous immunoglobulins and aspirin, then with methylprednisolone which led to fever remission. The same child was re-hospitalized after a 10-month-period of well-being for the suspicion of a new episode of Kawasaki syndrome, which appeared to be immunoglobulin-resistant: extensive testing failed to provide an alternative diagnosis of any infectious or infiltrative disease. Diagnosis of systemic onset-juvenile idiopathic arthritis was postulated upon the long persistence of fever and inflammatory signs, which subsided only after starting corticosteroid treatment.
ISSN:0172-8172
1437-160X
DOI:10.1007/s00296-009-0960-1