Comparative Activity of Pradofloxacin, Enrofloxacin, and Azithromycin against Bartonella henselae Isolates Collected from Cats and a Human

Using Bartonella henselae isolates from cats and a human, the activity of pradofloxacin was compared with those of enrofloxacin and azithromycin. By Etest and disc diffusion assay, pradofloxacin showed greater antimicrobial activity than did other antibiotics. We conclude that pradofloxacin may prov...

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Bibliographic Details
Published in:Journal of Clinical Microbiology 2010-02, Vol.48 (2), p.617-618
Main Authors: Biswas, Silpak, Maggi, Ricardo G, Papich, Mark G, Keil, Daniel, Breitschwerdt, Edward B
Format: Article
Language:English
Subjects:
Angiomatosis, Bacillary - microbiology
Angiomatosis, Bacillary - veterinary
Animals
Anti-Bacterial Agents - pharmacology
Azithromycin - pharmacology
Bacteriology
Bartonella henselae
Bartonella henselae - drug effects
Bartonella henselae - isolation & purification
Biological and medical sciences
Cat Diseases - microbiology
Cat-Scratch Disease - microbiology
Cats
Clinical Veterinary Microbiology
Fluoroquinolones - pharmacology
Fundamental and applied biological sciences. Psychology
Humans
Microbial Sensitivity Tests
Microbiology
Miscellaneous
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Summary:Using Bartonella henselae isolates from cats and a human, the activity of pradofloxacin was compared with those of enrofloxacin and azithromycin. By Etest and disc diffusion assay, pradofloxacin showed greater antimicrobial activity than did other antibiotics. We conclude that pradofloxacin may prove useful for the treatment of B. henselae infections.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.01287-09