A clinical review of 105 patients with PFAPA (a periodic fever syndrome)

Aims:  We describe the presentations and clinical outcomes of pediatric patients diagnosed with PFAPA (Periodic Fever, Aphthous lesions, Pharyngitis, and cervical Adenitis). Materials and methods:  The medical records of children with recurrent fever and referred between 1998 and 2007 to a tertiary...

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Bibliographic Details
Published in:Acta Paediatrica 2010-02, Vol.99 (2), p.178-184
Main Authors: Feder, HM, Salazar, JC
Format: Article
Language:English
Subjects:
aphthous
Biological and medical sciences
Child, Preschool
Cimetidine - therapeutic use
Diseases of the osteoarticular system
Facial bones, jaws, teeth, parodontium: diseases, semeiology
Female
Fever - therapy
General aspects
Histamine H2 Antagonists - therapeutic use
Humans
Inflammatory joint diseases
Lymphadenitis
Male
Medical sciences
Non tumoral diseases
Otorhinolaryngology. Stomatology
periodic fever
Periodicity
PFAPA
Pharyngitis
Stomatitis, Aphthous
Syndrome
Tonsillectomy
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Summary:Aims:  We describe the presentations and clinical outcomes of pediatric patients diagnosed with PFAPA (Periodic Fever, Aphthous lesions, Pharyngitis, and cervical Adenitis). Materials and methods:  The medical records of children with recurrent fever and referred between 1998 and 2007 to a tertiary pediatric care hospital were reviewed. Children who met clinical criteria for PFAPA were then asked to participate in a follow‐up study. Results:  One hundred and five children met study criteria for PFAPA which included at least six episodes of periodic fever. Most (62%) were males, the mean age at onset of PFAPA was 39.6 months (80% were
ISSN:0803-5253
1651-2227
DOI:10.1111/j.1651-2227.2009.01554.x