Movement disorder: A manifestation of HIV and its response to therapy

Both akinetic and hyperkinetic movement disorders may rarely be the presenting feature of human immunodeficiency virus (HIV) infection. The possible pathogenic basis is the involvement of subcortical structures by the HIV infection-related pathology. Opportunistic infections, or mass lesions complic...

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Bibliographic Details
Published in:Neurology India 2009-11, Vol.57 (6), p.789-791
Main Authors: Sankhla, Charulata S, Soman, Rajeev N, Gupta, Neha N, Shah, Pratik V
Format: Article
Language:English
Subjects:
Anti-retroviral therapy, human immunodeficiency virus, movement disorder
Antiretroviral Therapy, Highly Active - methods
Antiviral agents
Care and treatment
Case studies
Complications and side effects
Diagnosis
Drug therapy
Health aspects
HIV
HIV infection
HIV Infections - complications
HIV Infections - drug therapy
HIV Infections - pathology
Human immunodeficiency virus
Humans
Magnetic Resonance Imaging - methods
Male
Medical imaging
Middle Aged
Movement disorders
Movement Disorders - drug therapy
Movement Disorders - etiology
Movement Disorders - pathology
Movement Disorders - virology
Patients
Risk factors
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Summary:Both akinetic and hyperkinetic movement disorders may rarely be the presenting feature of human immunodeficiency virus (HIV) infection. The possible pathogenic basis is the involvement of subcortical structures by the HIV infection-related pathology. Opportunistic infections, or mass lesions complicating HIV infection. In addition dopaminergic dysfunction and medications may also play a role. We report a HIV infected male who presented with progressive choreoathetoid movements and dystonia. He had remarkable improvement of the movement disorder with tetrabenazine and anti-retroviral therapy (HAART) treatment.
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.59480