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Production of alginate beads by emulsification/internal gelation. I. Methodology
Small diameter alginate beads (microspheres) were formed via internal gelation of alginate solution emulsified within vegetable oil. Gelation was initiated by addition of an oil-soluble acid thereby reducing the pH of the alginate solution and releasing soluble Ca2+ from the citrate complex. Smooth,...
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Published in: | Applied microbiology and biotechnology 1992-10, Vol.38 (1), p.39-45 |
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container_issue | 1 |
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container_title | Applied microbiology and biotechnology |
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creator | Poncelet, D Lencki, R Beaulieu, C Halle, J P Neufeld, R J Fournier, A |
description | Small diameter alginate beads (microspheres) were formed via internal gelation of alginate solution emulsified within vegetable oil. Gelation was initiated by addition of an oil-soluble acid thereby reducing the pH of the alginate solution and releasing soluble Ca2+ from the citrate complex. Smooth, spherical, micron-sized beads were formed. The mean diameter ranged from 200 to 1000 microns, controlled by the reactor impeller design and rotational speed. The technique has potential for large-scale and continuous applications in immobilization. |
doi_str_mv | 10.1007/BF00169416 |
format | article |
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subjects | Alginates Biotechnology Chemical Phenomena Chemistry, Physical Drug Compounding - instrumentation Drug Compounding - methods Emulsions Fatty Acids, Monounsaturated Gels Glucuronic Acid Hexuronic Acids Microspheres Particle Size Rapeseed Oil Solubility |
title | Production of alginate beads by emulsification/internal gelation. I. Methodology |
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