Chronic kidney disease is associated with incident cognitive impairment in the elderly: the INVADE study

Background. Limited data exist regarding the relationship between decreased renal function and cognitive impairment. Methods. A total of 3679 participants of the Intervention Project on Cerebrovascular Diseases and Dementia in the Community of Ebersberg (INVADE) composed the community-based cohort s...

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Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 2009-10, Vol.24 (10), p.3144-3150
Main Authors: Etgen, Thorleif, Sander, Dirk, Chonchol, Michel, Briesenick, Claus, Poppert, Holger, Förstl, Hans, Bickel, Horst
Format: Article
Language:English
Subjects:
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Chronic Disease
chronic kidney disease
Cognition Disorders - etiology
cognitive impairment
elderly
Emergency and intensive care: renal failure. Dialysis management
Female
Humans
Intensive care medicine
Kidney Diseases - complications
Male
Medical sciences
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Prospective Studies
Renal failure
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Summary:Background. Limited data exist regarding the relationship between decreased renal function and cognitive impairment. Methods. A total of 3679 participants of the Intervention Project on Cerebrovascular Diseases and Dementia in the Community of Ebersberg (INVADE) composed the community-based cohort study. Measures of renal function were estimated using the Cockcroft–Gault equation and divided into normal, mild and moderate-to-severe impaired renal function (creatinine clearance ≥60, 45–59 and
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/gfp230