Profiling type I collagen gene expression in growing mandibular structures

We conducted a temporal gene expression analysis with type I collagen in the coronoid process, alveolar process and mandibular angle of the rat. We observed gene expression cross-sectionally across different important physiological time points in the rat postnatal life in order to observe in which d...

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Bibliographic Details
Published in:Annals of anatomy 2010-04, Vol.192 (2), p.96-100
Main Authors: Römer, P., Weingärtner, J., Proff, P., Roldán, J.C., Reicheneder, C.
Format: Article
Language:English
Subjects:
Actins - genetics
Alveolar Process - anatomy & histology
Alveolar Process - growth & development
Alveolar Process - metabolism
Animals
Collagen
Collagen Type I - genetics
Craniofacial growth
DNA Primers
Extracellular matrix
Gene Expression Regulation
Male
Mandible - anatomy & histology
Mandible - growth & development
Mandible - metabolism
Mandibular growth
Rats
Rats, Inbred Lew
Reverse Transcriptase Polymerase Chain Reaction
RNA - genetics
RNA, Messenger - genetics
Sexual Maturation
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Summary:We conducted a temporal gene expression analysis with type I collagen in the coronoid process, alveolar process and mandibular angle of the rat. We observed gene expression cross-sectionally across different important physiological time points in the rat postnatal life in order to observe in which developmental stage mandibular development mainly occur. This study indicates prominent type I collagen expression at day 10 postpartum in the mandibular ramus and at day 21 in the alveolar process. These findings correspond well with previously obtained data from proliferation studies in facial bone suggesting that craniofacial growth in the rat occurs mainly between days 10 and 21.
ISSN:0940-9602
1618-0402
DOI:10.1016/j.aanat.2009.12.002