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Arterio-venous shunts or low oxygen utilization?

An idea of arteriovenous shunts (AVS) was proposed for explanation of dynamic regulation of oxygenation and venous hyperoxia. A formula enabling calculation of AVS and real CO 2 production has recently been derived by comparing data of arterial and venous blood gases. Regarding venous hyperoxia, the...

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Bibliographic Details
Published in:Human & experimental toxicology 2010-02, Vol.29 (2), p.141-144
Main Author: Rozin, Alexander P
Format: Article
Language:English
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Summary:An idea of arteriovenous shunts (AVS) was proposed for explanation of dynamic regulation of oxygenation and venous hyperoxia. A formula enabling calculation of AVS and real CO 2 production has recently been derived by comparing data of arterial and venous blood gases. Regarding venous hyperoxia, there is a need to differentiate capillary to tissue transport defect (low oxygen utilisation-LOU) from AVS, which may exist simultaneously. The AVS may be associated with normal or relatively high oxygen utilization from the capillary vessels and increased CO2 production. AVS is proposed to carry protective and ‘stealing’ properties including renal, cardiac, and pulmonary hemodynamic. Calculations of the AVS may be important for dynamic assessment of vascular and metabolic status and in emergency medicine.
ISSN:0960-3271
1477-0903
DOI:10.1177/0960327109357216